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CAY10526

Product Name
CAY10526
CAS No.
938069-71-7
Chemical Name
CAY10526
Synonyms
CAY10526;CAY10526 Exclusive;2(5H)-Furanone, 4-benzo[b]thien-2-yl-3-bromo-5-hydroxy-;3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one;4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one;WM793,PGE2 production,Inhibitor,inhibit,SB2,microsomal PGE2 synthase-1,A375,cleaved caspase 3,CAY10526,increases apoptosis,increases BAX and BAK,pro-apoptotic,anti-apoptotic,melanoma xenografts,mPGES1 inhibitor,PGE synthase,Prostaglandin E synthase
CBNumber
CB82590422
Molecular Formula
C12H7BrO3S
Formula Weight
311.15
MOL File
938069-71-7.mol
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CAY10526 Property

Boiling point:
561.7±50.0 °C(Predicted)
Density 
1.889±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml
form 
A crystalline solid
pka
8.90±0.60(Predicted)
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010088
Product name
CAY10526
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
10010088
Product name
CAY10526
Purity
≥98%
Packaging
5mg
Price
$249
Updated
2024/03/01
Cayman Chemical
Product number
10010088
Product name
CAY10526
Purity
≥98%
Packaging
10mg
Price
$437
Updated
2024/03/01
AK Scientific
Product number
1400AH
Product name
4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one
Packaging
1mg
Price
$160
Updated
2021/12/16
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CAY10526 Chemical Properties,Usage,Production

Description

Prostaglandin E2 (PGE2) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE2 during inflammation can be accounted for by increased expression of both cyclooxygenase-2 (COX-2) and microsomal PGE synthase-1 (mPGES-1). CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression. It dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression.

CAY10526 Preparation Products And Raw materials

Raw materials

Preparation Products

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CAY10526 Suppliers

China 43 United States 3 Global 46
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

938069-71-7, CAY10526Related Search:


  • CAY10526
  • CAY10526 Exclusive
  • 3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one
  • 2(5H)-Furanone, 4-benzo[b]thien-2-yl-3-bromo-5-hydroxy-
  • WM793,PGE2 production,Inhibitor,inhibit,SB2,microsomal PGE2 synthase-1,A375,cleaved caspase 3,CAY10526,increases apoptosis,increases BAX and BAK,pro-apoptotic,anti-apoptotic,melanoma xenografts,mPGES1 inhibitor,PGE synthase,Prostaglandin E synthase
  • 4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one
  • 938069-71-7