ChemicalBook > CAS DataBase List > 4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-

4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-

Product Name
4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-
CAS No.
676266-31-2
Chemical Name
4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-
Synonyms
Sudoterb;Sudoterb free;Sudoterb (LL3858);Sudoterb free base;N-(2-Methyl-5-phenyl-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methyl)-1H-pyrrol-1-yl)isonicotinamide;4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-
CBNumber
CB82627090
Molecular Formula
C29H28F3N5O
Formula Weight
519.56
MOL File
676266-31-2.mol
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4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- Property

Density 
1.27±0.1 g/cm3(Predicted)
pka
4.77±0.46(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0316613
Product name
N-[2-METHYL-5-PHENYL-3-[[4-[3-(TRIFLUOROMETHYL)PHENYL]-1-PIPERAZINYL]METHYL]-1H-PYRROL-1-YL]-4-PYRIDINECARBOXAMIDE
Purity
95.00%
Packaging
5MG
Price
$496.21
Updated
2021/12/16
DC Chemicals
Product number
DC11534
Product name
Sudoterb
Purity
>98%
Packaging
100mg
Price
$750
Updated
2021/12/16
DC Chemicals
Product number
DC11534
Product name
Sudoterb
Purity
>98%
Packaging
250mg
Price
$1200
Updated
2021/12/16
DC Chemicals
Product number
DC11534
Product name
Sudoterb
Purity
>98%
Packaging
1g
Price
$2400
Updated
2021/12/16
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4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- Chemical Properties,Usage,Production

Uses

Sudoterb (LL 3858) is an orally active anti-Tuberculosis agent[1].

in vivo

Sudoterb (12.5 mg/kg and 25 mg/kg, p.o., 4 and 8 weeks) is effective against M.tuberculosis in mice[2].
Sudoterb (p.o., mice) shows a LD50 of 700 mg/kg[2].

References

[1] Maha A. Elhakeem, et al. Synthesis and anti-mycobacterial evaluation of some new isonicotinylhydrazide analogues. Bulletin of Faculty of Pharmacy, Cairo University. 2015, 53 (1), 45-52
[2] Protopopova M, et al. In search of new cures for tuberculosis. Med Chem. 2007 May;3(3):301-16. DOI:10.2174/157340607780620626

4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- Suppliers

China 25 United States 2 Global 27
Nanjing Norris-Pharm Technology Co., Ltd
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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
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InvivoChem
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676266-31-2, 4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-Related Search:


  • 4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]-
  • Sudoterb
  • Sudoterb free base
  • Sudoterb (LL3858)
  • Sudoterb free
  • N-(2-Methyl-5-phenyl-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methyl)-1H-pyrrol-1-yl)isonicotinamide
  • 676266-31-2
  • C29H28F3N5O