ChemicalBook > CAS DataBase List > FGH-10019
FGH-10019
- Product Name
- FGH-10019
- CAS No.
- 1046045-61-7
- Chemical Name
- FGH-10019
- Synonyms
- FGH-10019;FGH10019, 10 mM in DMSO;FGH10019;FGH-10019;FGH 10019;FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN);N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide;Methanesulfonamide, N-[4-[2-(2-propyl-4-pyridinyl)-4-thiazolyl]phenyl]-
- CBNumber
- CB82627883
- Molecular Formula
- C18H19N3O2S2
- Formula Weight
- 373.49
- MOL File
- 1046045-61-7.mol
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FGH-10019 Property
- Boiling point:
- 578.4±60.0 °C(Predicted)
- Density
- 1.307±0.06 g/cm3(Predicted)
- pka
- 7.16±0.10(Predicted)
- form
- Solid
- color
- Light yellow to khaki
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-3637
- Product name
- FGH10019
- Purity
- 99.43%
- Packaging
- 10mg
- Price
- $480
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3637
- Product name
- FGH10019
- Purity
- 99.43%
- Packaging
- 5mg
- Price
- $330
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3637
- Product name
- FGH10019
- Purity
- 99.43%
- Packaging
- 50mg
- Price
- $1440
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31004727
- Product name
- FGH10019
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $1459
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC26143
- Product name
- FGH10019
- Purity
- >98%
- Packaging
- 1g
- Price
- $2600
- Updated
- 2021/12/16
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FGH-10019 Chemical Properties,Usage,Production
Uses
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.
in vivo
FGH10019-treated chow is fed at a dose rate calculated to provide about 0.7 mg analog FGH10019 per day, at about 23 mg/kg body weight, to 5-wk-old male ob/ob mice weighing an average of appr 30 g. After 8 wk on the analog 24-treated chow, the mice gain 8-9 % less weight than control mice[1].
References
[1] Kamisuki S, et al. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. J Med Chem. 2011 Jul 14;54(13):4923-7. DOI:10.1021/jm200304y
FGH-10019 Preparation Products And Raw materials
Raw materials
Preparation Products
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FGH-10019 Suppliers
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- +1-800-259-7612
- Fax
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- United States
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