Censavudine
- Product Name
- Censavudine
- CAS No.
- 634907-30-5
- Chemical Name
- Censavudine
- Synonyms
- OBP601;4'-Ed4T;OBP 601;OBP-601;BMS 986001;Festinavir;Censavudine;2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine;Thymidine, 2',3'-didehydro-3'-deoxy-4'-ethynyl-
- CBNumber
- CB82717753
- Molecular Formula
- C12H12N2O4
- Formula Weight
- 248.24
- MOL File
- 634907-30-5.mol
Censavudine Property
- Melting point:
- 207-209℃
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, away from moisture
- solubility
- DMSO : 52 mg/mL (209.48 mM; Need ultrasonic)
- pka
- 9.47±0.10(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- InChI
- InChI=1S/C12H12N2O4/c1-3-12(7-15)5-4-9(18-12)14-6-8(2)10(16)13-11(14)17/h1,4-6,9,15H,7H2,2H3,(H,13,16,17)/t9-,12+/m1/s1
- InChIKey
- OSYWBJSVKUFFSU-SKDRFNHKSA-N
- SMILES
- OC[C@@]1(C#C)O[C@@H](N2C=C(C)C(=O)NC2=O)C=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H341Suspected of causing genetic defects
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F321325
- Product name
- Festinavir
- Packaging
- 10mg
- Price
- $1320
- Updated
- 2021/12/16
Censavudine Chemical Properties,Usage,Production
Uses
Festinavir is a modified nucleoside which has been shown great in vitro activity against HIV-2. It has also been used as potent inhibitor against entecavir-resistant hepatitis B.
in vivo
The pharmacokinetic parameters of Censavudine (BMS-986001; 100-750 mg/kg) generated from the dried blood spot (DBS) assay and the plasma assay is compared. The ratios of the AUC(0-24 h) and C max for BMS-986001 in DBS compared to those in plasma are consistent at 0.83-0.91 and 0.81-0.97, respectively, across all dose groups in rats. The T max in rat DBS and plasma are also consistent at about 1 h[2].
IC 50
HIV-2: 30-81 nM (EC50); HIV-1: 450-890 nM (IC50)
Censavudine Preparation Products And Raw materials
Raw materials
Preparation Products
Censavudine Suppliers
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- 15658004993
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- China
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
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View Lastest Price from Censavudine manufacturers
- Product
- Censavudine 634907-30-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 97%
- Supply Ability
- 100g
- Release date
- 2024-12-16