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Censavudine

Product Name
Censavudine
CAS No.
634907-30-5
Chemical Name
Censavudine
Synonyms
OBP601;4'-Ed4T;OBP 601;OBP-601;BMS 986001;Festinavir;Censavudine;2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine;Thymidine, 2',3'-didehydro-3'-deoxy-4'-ethynyl-
CBNumber
CB82717753
Molecular Formula
C12H12N2O4
Formula Weight
248.24
MOL File
634907-30-5.mol
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Censavudine Property

Melting point:
207-209℃
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
4°C, away from moisture
solubility 
DMSO : 52 mg/mL (209.48 mM; Need ultrasonic)
pka
9.47±0.10(Predicted)
form 
Solid
color 
Light yellow to yellow
InChI
InChI=1S/C12H12N2O4/c1-3-12(7-15)5-4-9(18-12)14-6-8(2)10(16)13-11(14)17/h1,4-6,9,15H,7H2,2H3,(H,13,16,17)/t9-,12+/m1/s1
InChIKey
OSYWBJSVKUFFSU-SKDRFNHKSA-N
SMILES
OC[C@@]1(C#C)O[C@@H](N2C=C(C)C(=O)NC2=O)C=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
F321325
Product name
Festinavir
Packaging
10mg
Price
$1320
Updated
2021/12/16
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Censavudine Chemical Properties,Usage,Production

Uses

Festinavir is a modified nucleoside which has been shown great in vitro activity against HIV-2. It has also been used as potent inhibitor against entecavir-resistant hepatitis B.

in vivo

The pharmacokinetic parameters of Censavudine (BMS-986001; 100-750 mg/kg) generated from the dried blood spot (DBS) assay and the plasma assay is compared. The ratios of the AUC(0-24 h) and C max for BMS-986001 in DBS compared to those in plasma are consistent at 0.83-0.91 and 0.81-0.97, respectively, across all dose groups in rats. The T max in rat DBS and plasma are also consistent at about 1 h[2].

IC 50

HIV-2: 30-81 nM (EC50); HIV-1: 450-890 nM (IC50)

Censavudine Preparation Products And Raw materials

Raw materials

Preparation Products

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Censavudine Suppliers

China 23 United States 5 Global 28
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
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View Lastest Price from Censavudine manufacturers

NewCan Biotech Limited
Product
Censavudine 634907-30-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
97%
Supply Ability
100g
Release date
2024-12-16

634907-30-5, CensavudineRelated Search:


  • 2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine
  • 4'-Ed4T
  • BMS 986001
  • Censavudine
  • Festinavir
  • Thymidine, 2',3'-didehydro-3'-deoxy-4'-ethynyl-
  • OBP 601
  • OBP601
  • OBP-601
  • 634907-30-5