CARBOXYPEPTIDASE G
- Product Name
- CARBOXYPEPTIDASE G
- CAS No.
- 9074-87-7
- Chemical Name
- CARBOXYPEPTIDASE G
- Synonyms
- EC 3.4.19.9;Glucarpidase;CARBOXYPEPTIDASE G;γ-glutamyl hydrolase;GAMMA-GLUTAMYL HYDROLASE;Hydrolase, gamma-glutamyl;CARBOXYPEPTIDASE G FROM PSEUDOMONAS SP.;Native Pseudomonas sp. Carboxypeptidase G;carboxypeptidase G from pseudomonas sp. purificat;Carboxypeptidase G from Pseudomonas sp. lyophilized powder, >=3 units/mg protein
- CBNumber
- CB8278359
- Molecular Formula
- Zn4+8
- Formula Weight
- 261.56
- MOL File
- 9074-87-7.mol
CARBOXYPEPTIDASE G Property
- storage temp.
- -20°C
- solubility
- H2O: soluble0.5mg/mL
- form
- lyophilized powder
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C9658
- Product name
- Carboxypeptidase G from Pseudomonas sp.
- Purity
- lyophilized powder, ≥3?units/mg protein
- Packaging
- 5units
- Price
- $244
- Updated
- 2024/03/01
- Product number
- C9658
- Product name
- Carboxypeptidase G from Pseudomonas sp.
- Purity
- lyophilized powder, ≥3?units/mg protein
- Packaging
- 20units
- Price
- $728
- Updated
- 2024/03/01
- Product number
- 025240
- Product name
- Gamma-Glutamyl Hydrolase
- Packaging
- 96Tests
- Price
- $864
- Updated
- 2021/12/16
- Product number
- ENZ0000685
- Product name
- CARBOXYPEPTIDASE G-PSEUDOMONAS SP.
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.41
- Updated
- 2021/12/16
CARBOXYPEPTIDASE G Chemical Properties,Usage,Production
Uses
Carboxypeptidase G from Pseudomonas sp., or γ-Glutamyl hydrolase, has been used in a study to assess the role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations. Carboxypeptidase G from Pseudomonas sp. has also been used in a study to investigate the effects of nitric oxide on pemetrexed cytotoxicity via NO?cGMP signaling in lung adenocarcinoma cells.
Biochem/physiol Actions
Carboxypeptidase G is a lysosomal, thiol-dependent protease, which progressively cleaves γ-glutamyl pteroyl poly-γ-glutamate yielding pteroyl-α-glutamate (folic acid) and free glutamate. It is considered highly specific for the γ-glutamyl bond, but not for the C-terminal amino acid of the leaving group. Molecular mass of this homodimer is approximately 90 kDa. The enzyme is activated by Zn2+ ions.