Gemigliptin

Product Name: Gemigliptin
CAS No.: 1374639-74-3
Chemical Name: Gemigliptin
Synonyms: LC15-0444 tartrate;Gemigliptin Tartrate;Gemigliptin Tartrate(911637-19-9 free base);Gemigliptin (2R,3R)-2,3-dihydroxybutanedioate;Gemigliptin (2R,3R)-2,3-dihydroxybutanedioic acid;Gemigliptin Tartrate(911637-19-9 free base), 10 mM in DMSO;(s)-1-(2-amino-4-(2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6h)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one (2r,3r)-2,3-dihydroxysuccinate;type,Gemigliptin,products,mellitus,peptidase-4,Gemigliptin Tartrate(911637 19 9 free base),dipeptidyl,Gemigliptin Tartrate(911637199 free base),advanced,diabetes,Inhibitor,end,glycation,DPP,Dipeptidyl Peptidase,LC15-0444,AGE,inhibit
CBNumber: CB83116353
Molecular Formula: C22H25F8N5O8
Formula Weight: 639.46
MOL File: 1374639-74-3.mol

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Gemigliptin Property

storage temp.: Store at 0-8 °C
solubility: DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 1 mg/ml
form: A solid
color: Light yellow to orange

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0041582
Product name: Gemigliptin(tartrate)
Purity: 98.28%
Packaging: 10mg
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-0041582
Product name: Gemigliptin(tartrate)
Purity: 98.28%
Packaging: 50mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-0041582
Product name: Gemigliptin(tartrate)
Purity: 98.28%
Packaging: 100mg
Price: $520
Updated: 2021/12/16

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Gemigliptin Chemical Properties,Usage,Production

Uses

Gemigliptin (tartrate) may be useful in the study of pharmaceutical composition comprising gemigliptin for improving vascular endothelial function.

in vivo

Gemigliptin tartrate (100 mg/kg; i.g.; daily; for 12 weeks) inhibits AGEs formation and AGE cross-links in vivo^[1].
Gemigliptin tartrate dose-dependently inhibits plasma DPP-4 activity in rats, dogs, and monkeys^[2].

Animal Model:	Male C57BL/KsJ-db/db mice (7 weeks old)^[1]
Dosage:	100 mg/kg
Administration:	Oral gavage, daily, for 12 weeks
Result:	Significantly reduced circulating AGE levels by 44.5% in serum.

Gemigliptin Preparation Products And Raw materials

Raw materials

Preparation Products

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Gemigliptin Suppliers

China 31 United States 5 Global 36

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1374639-74-3, GemigliptinRelated Search:

Gemigliptin (2R,3R)-2,3-dihydroxybutanedioate

Gemigliptin Tartrate

Gemigliptin Tartrate(911637-19-9 free base)

LC15-0444 tartrate

type,Gemigliptin,products,mellitus,peptidase-4,Gemigliptin Tartrate(911637 19 9 free base),dipeptidyl,Gemigliptin Tartrate(911637199 free base),advanced,diabetes,Inhibitor,end,glycation,DPP,Dipeptidyl Peptidase,LC15-0444,AGE,inhibit

Gemigliptin (2R,3R)-2,3-dihydroxybutanedioic acid

Gemigliptin Tartrate(911637-19-9 free base), 10 mM in DMSO

(s)-1-(2-amino-4-(2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6h)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one (2r,3r)-2,3-dihydroxysuccinate

1374639-74-3