Gemigliptin
- Product Name
- Gemigliptin
- CAS No.
- 1374639-74-3
- Chemical Name
- Gemigliptin
- Synonyms
- LC15-0444 tartrate;Gemigliptin Tartrate;Gemigliptin Tartrate(911637-19-9 free base);Gemigliptin (2R,3R)-2,3-dihydroxybutanedioate;Gemigliptin (2R,3R)-2,3-dihydroxybutanedioic acid;Gemigliptin Tartrate(911637-19-9 free base), 10 mM in DMSO;(s)-1-(2-amino-4-(2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6h)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one (2r,3r)-2,3-dihydroxysuccinate;type,Gemigliptin,products,mellitus,peptidase-4,Gemigliptin Tartrate(911637 19 9 free base),dipeptidyl,Gemigliptin Tartrate(911637199 free base),advanced,diabetes,Inhibitor,end,glycation,DPP,Dipeptidyl Peptidase,LC15-0444,AGE,inhibit
- CBNumber
- CB83116353
- Molecular Formula
- C22H25F8N5O8
- Formula Weight
- 639.46
- MOL File
- 1374639-74-3.mol
Gemigliptin Property
- storage temp.
- Store at 0-8 °C
- solubility
- DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 1 mg/ml
- form
- A solid
- color
- Light yellow to orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0041582
- Product name
- Gemigliptin(tartrate)
- Purity
- 98.28%
- Packaging
- 10mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-0041582
- Product name
- Gemigliptin(tartrate)
- Purity
- 98.28%
- Packaging
- 50mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- CS-0041582
- Product name
- Gemigliptin(tartrate)
- Purity
- 98.28%
- Packaging
- 100mg
- Price
- $520
- Updated
- 2021/12/16
Gemigliptin Chemical Properties,Usage,Production
Uses
Gemigliptin (tartrate) may be useful in the study of pharmaceutical composition comprising gemigliptin for improving vascular endothelial function.
in vivo
Gemigliptin tartrate (100 mg/kg; i.g.; daily; for 12 weeks) inhibits AGEs formation and AGE cross-links in vivo[1].
Gemigliptin tartrate dose-dependently inhibits plasma DPP-4 activity in rats, dogs, and monkeys[2].
| Animal Model: | Male C57BL/KsJ-db/db mice (7 weeks old)[1] |
| Dosage: | 100 mg/kg |
| Administration: | Oral gavage, daily, for 12 weeks |
| Result: | Significantly reduced circulating AGE levels by 44.5% in serum. |
Gemigliptin Preparation Products And Raw materials
Raw materials
Preparation Products
Gemigliptin Suppliers
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