ChemicalBook > CAS DataBase List > 2-Amino-4-(trifluoromethyl)pyrimidine

2-Amino-4-(trifluoromethyl)pyrimidine

Product Name
2-Amino-4-(trifluoromethyl)pyrimidine
CAS No.
16075-42-6
Chemical Name
2-Amino-4-(trifluoromethyl)pyrimidine
Synonyms
DM6-Sme;AKOS B024896;BUTTPARK 27\08-65;ART-CHEM-BB B024896;4-TrifluoroMethyl-2-aMinopyriMidine;2-Amino-4-(trifluoromethyl)pyrimdine;4-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE;4-(Trifluoromethyl)-2-pyrimidinamine;2-AMINO-4-(TRIFLUOROMETHYL)PYRIMIDINE;4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YLAMINE
CBNumber
CB8397302
Molecular Formula
C5H4F3N3
Formula Weight
163.1
MOL File
16075-42-6.mol
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2-Amino-4-(trifluoromethyl)pyrimidine Property

Melting point:
175-177°C
Boiling point:
260.7±50.0 °C(Predicted)
Density 
1.460±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
1.90±0.10(Predicted)
color 
White to Light yellow
λmax
308nm(EtOH aq.)(lit.)
CAS DataBase Reference
16075-42-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,N,T
Risk Statements 
36/37/38-50-43-36-25
Safety Statements 
26-36/37/39-61-45-36/37
RIDADR 
2811
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
Ⅲ
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
709131
Product name
2-Amino-4-(trifluoromethyl)pyrimidine
Purity
97%
Packaging
1g
Price
$64.1
Updated
2023/06/20
TCI Chemical
Product number
A2522
Product name
2-Amino-4-(trifluoromethyl)pyrimidine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$46
Updated
2025/07/31
TCI Chemical
Product number
A2522
Product name
2-Amino-4-(trifluoromethyl)pyrimidine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$184
Updated
2025/07/31
TRC
Product number
A633473
Product name
2-Amino-4-(trifluoromethyl)pyrimidine
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-3-X0
Product name
2-Amino-4-(trifluoromethyl)pyrimidine
Purity
97%
Packaging
25g
Price
$90
Updated
2021/12/16
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2-Amino-4-(trifluoromethyl)pyrimidine Chemical Properties,Usage,Production

Chemical Properties

White to brown powder

Synthesis

59938-06-6

113-00-8

16075-42-6

Step 2: To a solution of compound [63] (22.8 g, 2.4 mmol, 1 eq.) in anhydrous ethanol (100 mL), NaOH granules (9.55 g, 238 mmol, 1 eq.) were added and the reaction mixture was stirred for 16 h at room temperature. Subsequently, a solution of compound [84] was slowly added through a dropping funnel over a period of 2 hours. After addition, the reaction mixture was continued to be stirred for 2 hours. Upon completion of the reaction, the solvent was removed by evaporation and the residue was dissolved in water (500 mL) with vigorous stirring for 2 hours, followed by standing at room temperature overnight. The precipitate precipitated was collected by filtration and dried under vacuum to give compound [85] as a light yellow solid (20.6 g, 53% yield).

References

[1] Patent: WO2014/16849, 2014, A2. Location in patent: Page/Page column 117

2-Amino-4-(trifluoromethyl)pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4-(trifluoromethyl)pyrimidine Suppliers

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View Lastest Price from 2-Amino-4-(trifluoromethyl)pyrimidine manufacturers

LY Global chemicals co.,ltd .
Product
2-Amino-4-(trifluoromethyl)pyrimidine 16075-42-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100kg
Release date
2023-03-19
Honest Joy Holdings Limited
Product
2-Amino-4-(trifluoromethyl)pyrimidine 16075-42-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.2%
Supply Ability
100 tons
Release date
2022-02-08
Dideu Industries Group Limited
Product
2-Amino-4-(trifluoromethyl)pyrimidine 16075-42-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-10

16075-42-6, 2-Amino-4-(trifluoromethyl)pyrimidineRelated Search:

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  • 4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YLAMINE
  • AKOS B024896
  • ART-CHEM-BB B024896
  • BUTTPARK 27\08-65
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  • 2-AMino-4-(trifluoroMethyl)pyriMidine SynonyMs 4-(TrifluoroMethyl)-2-pyriMidinaMine
  • 4-(Trifluoromethyl)-2-pyrimidinamine
  • 4-TrifluoroMethyl-2-aMinopyriMidine
  • 2-Amino-4-(trifluoromethyl)pyrimidine,99%
  • 2-Amino-4-(trifluoromethyl)pyrimidine &gt
  • 2-Pyrimidinamine, 4-(trifluoromethyl)-
  • 2-Amino-4-(trifluoromethyl)pyrimidine ISO 9001：2015 REACH
  • 2-Thiazolamine,5-bromo-,hydrobromide(1:6)
  • DM6-Sme
  • 16075-42-6
  • C5H4F3N3
  • Fluorine series
  • Imidazoles & Benzimidazoles
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyrimidine series
  • Amines
  • Pyrazines, Pyrimidines & Pyridazines
  • Imidazoles & Benzimidazoles