ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- Product Name
- ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- CAS No.
- 53090-46-3
- Chemical Name
- ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- Synonyms
- ETHYL-3-THIOPHENOYL-ACETATE;Ethyl 3-oxo-3-(3-thienyl)propionate;2-[oxo(3-thiophenyl)methyl]butanoate;Ethyl 3-oxo-3-(thien-3-yl)propanoate;ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE;3-Thiophenepropanoic acid, β-oxo-, ethyl ester
- CBNumber
- CB8707679
- Molecular Formula
- C9H10O3S
- Formula Weight
- 198.24
- MOL File
- 53090-46-3.mol
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Property
- storage temp.
- 2-8°C(protect from light)
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P000269464
- Product name
- Ethyl 3-oxo-3-(thiophen-3-yl)propanoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $101
- Updated
- 2021/12/16
- Product number
- P000269464
- Product name
- Ethyl 3-oxo-3-(thiophen-3-yl)propanoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $327
- Updated
- 2021/12/16
- Product number
- 7525AB
- Product name
- Ethyl3-oxo-3-(thiophen-3-yl)propanoate
- Packaging
- 250mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- 7525AB
- Product name
- Ethyl3-oxo-3-(thiophen-3-yl)propanoate
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CHM0151880
- Product name
- ETHYL-3-OXO-3-(THIOPHEN-3-YL)PROPANOATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.79
- Updated
- 2021/12/16
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Chemical Properties,Usage,Production
Synthesis
1468-83-3
53090-46-3
General procedure for the synthesis of ethyl 3-oxo-3-(3-thienyl)propionate from 3-acetylthiophene: First, diethyl carbonate (36.3 mL, 300 mmol) was dissolved in toluene (18 mL) and the solution was heated to 60 °C. At this temperature, potassium tert-butoxide (13.0 g, 120 mmol) was added in batches, and after the addition, the reaction mixture was continued to be heated at 65°C for half an hour. Subsequently, the temperature was raised to 75 °C and a solution of 3-methylthiophene (9.2 g, 73 mmol) in toluene (18 mL) was slowly added dropwise. After the dropwise addition, the reaction mixture was heated at 80 °C for 90 min. After completion of the reaction, it was cooled to room temperature, the precipitated solid was collected by filtration and washed thoroughly with ether. The resulting solid was dissolved in water and extracted successively with ethyl acetate. The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate, filtered and the solvent was evaporated to give the dark oily product ethyl 3-oxo-3-(3-thienyl)propionate (12.0 g, 83% yield). The NMR hydrogen spectrum (CDCl3) data of the product were as follows: δ 1.25 (t, 3H), 3.90 (s, 2H), 4.20 (q, 2H), 7.35 (m, 1H), 7.55 (m, 1H), 8.10 (m, 1H).
References
[1] Patent: WO2005/123693, 2005, A1. Location in patent: Page/Page column 57-58
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 3-OXO-3-(THIOPHEN-3-YL)PROPANOATE Suppliers
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 021-58388037;21-58388037 13472507714
- 35177634@qq.com;1589045147@qq.com
- Country
- China
- ProdList
- 803
- Advantage
- 55
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4962
- Advantage
- 50
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-58851090 15955137747
- Fax
- (6)02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15949
- Advantage
- 58