FURIN INHIBITOR II

Product Name: FURIN INHIBITOR II
CAS No.: 673202-67-0
Chemical Name: FURIN INHIBITOR II
Synonyms: H-(D)RRRRRR-NH2;HEXA-D-ARGININE;FURIN INHIBITOR II;Hexa-D-arginine aMide;Hexa-D-arginine,RRRRRR;Furin Inhibitor II, >98%;Furin Inhibitor II(Hexa-D-arginine);H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
CBNumber: CB8719126
Molecular Formula: C36H75N25O6
Formula Weight: 954.14
MOL File: 673202-67-0.mol

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FURIN INHIBITOR II Property

Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
form: lyophilized
pka: 13.24±0.46(Predicted)
color: White to off-white
Water Solubility: Soluble to 2 mg/ml in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SCP0148
Product name: Furin Inhibitor II
Packaging: 5MG
Price: $268
Updated: 2023/06/20

Tocris

Product number: 4711
Product name: Hexa-D-arginine
Packaging: 1
Price: $124
Updated: 2021/12/16

TRC

Product number: H951018
Product name: Hexa-D-arginine
Packaging: 1mg
Price: $115
Updated: 2021/12/16

Usbiological

Product number: 145676
Product name: Hexa-D-arginine
Packaging: 1mg
Price: $375
Updated: 2021/12/16

ApexBio Technology

Product number: B5692
Product name: (R)-2-amino-5-((diaminomethylene)amino)-N-((6R,9R,12R,15R,18R)-1,1,23,23-tetraamino-6-carbamoyl-9,12,15-tris(3-((diaminomethylene)amino)propyl)-8,11,14,17-tetraoxo-2,7,10,13,16,22-hexaazatricosa-1,22-dien-18-yl)pentanamide
Packaging: 1mg
Price: $143
Updated: 2021/12/16

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FURIN INHIBITOR II Chemical Properties,Usage,Production

Uses

Furin Inhibitor II has been used as a furin inhibitor:

to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
in furin cleavage assay.

General Description

Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.

Biochem/physiol Actions

Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).

storage

Store at -20°C

FURIN INHIBITOR II Preparation Products And Raw materials

Raw materials

Preparation Products

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FURIN INHIBITOR II Suppliers

China 64 United Kingdom 2 United States 10 Global 76

MedChemexpress LLC

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Creative Peptides

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Alfa Chemistry

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Aladdin Scientific

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TargetMol Chemicals Inc.

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ApexBio Technology

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MedChemExpress

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EMD Biosciences, Inc.

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View Lastest Price from FURIN INHIBITOR II manufacturers

Career Henan Chemical Co

Product: FURIN INHIBITOR II 673202-67-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

673202-67-0, FURIN INHIBITOR IIRelated Search:

H-GLU-LEU-ASP-[(2R,4S,5S)-5-AMINO-4-HYDROXY-2,7-DIMETHYL-OCTANOYL]-VAL-GLU-PHE-GLY-GLY-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-OH FURIN INHIBITOR II C(NPYS)RRRRRRRRR-NH2

HEXA-D-ARGININE

H-(D)RRRRRR-NH2

FURIN INHIBITOR II

H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2

Hexa-D-arginine aMide

D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine

Furin Inhibitor II, >98%

Hexa-D-arginine,RRRRRR

D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)

D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-

inhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDarginine,Hexa D arginine,exotoxins,Inhibitor

Furin Inhibitor II(Hexa-D-arginine)

673202-67-0

C36H75N25O6