Pinacolborane

Product Name: Pinacolborane
CAS No.: 25015-63-8
Chemical Name: Pinacolborane
Synonyms: HBpin;4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;PINB;4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane;DK697;Nachoborane;PINACOLBORANE;Pinacolboronane;Pinacolborane 1;Pinacolatoborane
CBNumber: CB8745950
Molecular Formula: C6H13BO2
Formula Weight: 127.98
MOL File: 25015-63-8.mol

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Pinacolborane Property

Boiling point:: 42-43 °C50 mm Hg(lit.)
Density: 0.882 g/mL at 25 °C(lit.)
vapor pressure: 29-119.9hPa at 20-50℃
refractive index: n20/D 1.396(lit.)
Flash point:: 41 °F
storage temp.: 2-8°C
solubility: Miscible with ether, dichloromethane, tetrahydrofuran and organic solvents.
form: Liquid
Specific Gravity: 0.882
color: Clear colorless to light yellow
Sensitive: Air Sensitive
BRN: 7802871
Stability:: Air Sensitive, Hygroscopic, Moisture Sensitive
InChI: InChI=1S/C6H13BO2/c1-5(2)6(3,4)9-7-8-5/h7H,1-4H3
InChIKey: UCFSYHMCKWNKAH-UHFFFAOYSA-N
SMILES: O1C(C)(C)C(C)(C)OB1
CAS DataBase Reference: 25015-63-8(CAS DataBase Reference)

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Safety

Hazard Codes: F,Xi,Xn
Risk Statements: 11-15-36/37/38-36/37-19-40
Safety Statements: 16-43-8-37/39-26-33-29-36/37
RIDADR: UN 3398 4.3/PG 2
WGK Germany: 3
Hazard Note: Highly Flammable/Keep Cold/Air Sensitive
HazardClass: 4.3
PackingGroup: II
HS Code: 29209090
Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
Hazard Classifications: Flam. Liq. 2
Water-react 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H261In contact with water releases flammable gas

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P231+P232Handle under inert gas. Protect from moisture.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 458945
Product name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane solution
Purity: 1.0 M in THF
Packaging: 100ml
Price: $336.72
Updated: 2025/07/31

Sigma-Aldrich

Product number: 458945
Product name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane solution
Purity: 1.0 M in THF
Packaging: 4x25ml
Price: $336.72
Updated: 2025/07/31

TCI Chemical

Product number: T2572
Product name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane
Purity: >97.0%(GC)
Packaging: 5g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: T2572
Product name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane
Purity: >97.0%(GC)
Packaging: 25g
Price: $131
Updated: 2025/07/31

Sigma-Aldrich

Product number: 655856
Product name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane
Purity: 97%
Packaging: 5g
Price: $62.1
Updated: 2025/07/31

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Pinacolborane Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Uses

Pinacolborane is used as a precursor of boronic esters by hydroboration or coupling reactions. It acts as a monofunctional hydroborating agent. It is used in the synthesis of unsymmetrical biaryls through aromatic C-H borylation-cross-coupling sequence. It is involved in the preparation of 4,4,5,5-tetramethyl-2-thiophen-2-yl-[1,3,2]dioxaborolane by reacting with 2-iodo-thiophene. Further, it is used to prepare vinylboronates by palladium-catalyzed coupling with alkenyl triflates and iodides.

Uses

Pinacolborane is used for synthesis of unsymmetrical biaryls via aromatic C-H borylation-cross-coupling sequence.

Synthesis

Pinacol (177 g, 1.5 mol) and CH2Cl2 (1.6 L) were added to a 5 L round bottom flask. Borane dimethyl sulfide (10 M, 159 mL, 0.16 mol) was added to the flask via cannula and the mixture was stirred at 0??C for 4 hours. The reaction mixture was then heated to room temperature overnight with stirring.17 After 17 h, the reaction mixture gave off some gas (hydrogen); however, the reaction was heated and slowly depressurized (760 mm to 200 mm). This process allowed CH2Cl2 (1.3 L) to move away from the reaction. The remaining liquid was transferred to a 500 mL flask through a cannula and the pressure was slowly reduced from atmospheric to 50 mm over 2.5 h. Some initial foaming was observed in the viscous liquid due to continued outgassing. The method provided pinacol borane suitable for subsequent reactions. The yield was 157 g, 81.7%.

Pinacolborane Preparation Products And Raw materials

Raw materials

Pinacol Borane-methyl sulfide complex Dichloromethane

Preparation Products

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 3-MORPHOLINOPHENYLBORONIC ACID PINACOL ESTER 2-Ethoxycarbonylphenylboronic acid pinacol ester

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Pinacolborane Suppliers

Belgium 1 Canada 1 China 206 Germany 3 India 7 Japan 2 Russia 1 Switzerland 1 United Kingdom 5 United States 21 Global 248

Shanghai Forxine Pharmaceutical Co., Ltd.

Tel: 21-21-64961388 18918697718
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Shanghai Boyle Chemical Co., Ltd.

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J & K SCIENTIFIC LTD.

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Beijing Donghualituo Techonlogy Development Co.,Ltd.

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TCI (Shanghai) Development Co., Ltd.

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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View Lastest Price from Pinacolborane manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Pinacolborane 25015-63-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Hebei Fengqiang Trading Co., LTD

Product: Pinacolborane 25015-63-8
Price: US $100.00/bag
Min. Order: 1bag
Purity: 99
Supply Ability: 5000
Release date: 2023-08-30

Hubei Aumei New Material Co., Ltd.

Product: Pinacolborane 25015-63-8
Price: US $29.99/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50ton
Release date: 2021-09-01

25015-63-8, PinacolboraneRelated Search:

Bis(pinacolato)diboron 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Diborane METHYLCYCLOPENTADIENE DIMER 1,3-Dioxolane 1,4-Dioxane Borane-tetrahydrofuran complex Methoxydiethylborane Methyl cyclopentenolone Pentaborane 4'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE METHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE 4-Carboxylphenylboronic acid pinacol ester Allylboronic acid pinacol ester (2-BROMOMETHYLPHENYL)BORONIC ACID, PINACOL ESTER 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 2-Furanboronic acid pinacol ester

Pinacolatoborane

TetraMethyl-1,3,2-dioxab

Pinacolborane, 97%, stabilized

4,4,5,5-TetraMethyl-1,3,2-dioxaborolane 97%

4,4,5,5-TetraMethyl-1,3,2-dioxaborolane solution 1.0 M in THF

Pinacolborane (4,4,5,5-Tetramethyl-1,3,2-dioxaborolane)

4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

PINACOLBORANE

4,4,5,5-Tetramethyl-1,3,2-dioxaborolane,Pinacolborane

PINB

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Pinacolboronane

4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE, 1M SOLUTION IN TETRAHYDROFURAN

1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-

4,4,5,5-tetramethyl-1,3,2-dioxaborolane solution

Pinacolborane (PINB)

4,4,5,5-TETRAMETHYL-1,3,2-DIOXA- &

4,4,5,5-Tetramethyl-1,3-dioxa-2$l^{2}-boracyclopentane

4,4,5,5-Tetramethyl-1,3,2-dioxaborole

4,4,5,5-Tetramethyl-1,3-dioxa-2-boracyclopentane

Pinacolborane,97%

4,4,5,5-tetramethyl-1,3,2λ2-dioxaborolane

Pinacolborane, 1.0 M in THF, J&KSeal

4,4,5,5-Tetramethyl-1,3,2-dioxaborolane solution,Pinacolborane

HBpin

Pinacolborane, 97%, for synthesis

4,4,5,5-tetramethyl-1,3,2λsup2sup-dioxaborolane

Pinacolborane 1

4,4,5,5-tetramethyl-1,3,2

Nachoborane

DK697

4,4,5,5-tetramethyl-1,3,2$l^{2}-dioxaborolane

25015-63-8

250015-63-8

Organometallic Reagents

Boronic Acids and Derivatives

Borylation Reagents

Boron Derivatives

Heterocycles