ChemicalBook > CAS DataBase List > 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- Product Name
- 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- CAS No.
- 2154342-25-1
- Chemical Name
- 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- Synonyms
- Poma-C1-Alkyne;Pomalidomide-propargyl;Thalidomide-4-NH-propargyl;2-(2,6-Dioxo-3-piperidyl)-4-(2-propynylamino)isoindoline-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-
- CBNumber
- CB88374754
- Molecular Formula
- C16H13N3O4
- Formula Weight
- 311.29
- MOL File
- 2154342-25-1.mol
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1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Property
- Boiling point:
- 610.9±55.0 °C(Predicted)
- Density
- 1.496±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light, stored under nitrogen
- pka
- 10.73±0.40(Predicted)
- form
- Solid
- Appearance
- Light yellow to yellow Solid
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1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Chemical Properties,Usage,Production
Uses
Pomalidomide-propargyl contains an E3 ligand and a terminal alkyl group ready for click conjugation. Pomalidomide-propargyl is ready for conjugation to target proteins for PROTAC.
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Preparation Products And Raw materials
Raw materials
Preparation Products
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