ChemicalBook > CAS DataBase List > Baxdrostat
Baxdrostat
- Product Name
- Baxdrostat
- CAS No.
- 1428652-17-8
- Chemical Name
- Baxdrostat
- Synonyms
- RG-7641;CIN-107;RO-6836191;Baxdrostat;Baxdrostat, 10 mM in DMSO;(R)-N-(4-(1-Methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide;Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-;(+)-(R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide
- CBNumber
- CB89763124
- Molecular Formula
- C22H25N3O2
- Formula Weight
- 363.45
- MOL File
- 1428652-17-8.mol
More
Less
Baxdrostat Property
- Boiling point:
- 697.6±55.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- solubility
- DMSO : 250 mg/mL (687.85 mM; Need ultrasonic)
- pka
- 15.05±0.20(Predicted)
- form
- Solid
- color
- Off-white to light yellow
- InChI
- InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)/t19-/m1/s1
- InChIKey
- VDEUDSRUMNAXJG-LJQANCHMSA-N
- SMILES
- C(N[C@H]1C2=C(CCC1)C(C1C=CC3=C(C=1)CCC(=O)N3C)=CN=C2)(=O)CC
More
Less
Baxdrostat Chemical Properties,Usage,Production
Uses
Baxdrostat is a novel aldosterone synthase Inhibitor for treatment resistant hypertension and systemic Hypertension.
Mode of action
The mechanism of action of baxdrostat as an aldosterone synthase inhibitor demonstrates the inextricable linkage between sodium and blood pressure regulation. Baxdrostat significantly decreases aldosterone in plasma and urine, while increasing plasma renin as a physiological compensatory change.
Baxdrostat Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Baxdrostat Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58