ChemicalBook > CAS DataBase List > 3-Fluoro-5-bromobenzyl bromide

3-Fluoro-5-bromobenzyl bromide

Product Name: 3-Fluoro-5-bromobenzyl bromide
CAS No.: 216755-57-6
Chemical Name: 3-Fluoro-5-bromobenzyl bromide
Synonyms: 3-Fluoro-5-bromoben bromide;3-Fluoro-5-broMobenl broMide;5-bromo-3-fluorobenzyl bromide;3-Fluoro-5-bromobenzyl bromide;3-Bromo-5-fluorobenzylbromide,95%;3-Fluoride-5-Bromine Bromine Benzyl;1-Bromo-3-(bromomethyl)-5-fluorobenzene;Benzene, 1-bromo-3-(bromomethyl)-5-fluoro-;1-Bromo-3-(bromomethyl)-5-fluorobenzene, alpha,3-Dibromo-5-fluorotoluene
CBNumber: CB91139478
Molecular Formula: C7H5Br2F
Formula Weight: 267.92
MOL File: 216755-57-6.mol

Less

3-Fluoro-5-bromobenzyl bromide Property

Melting point:: 47 °C
Boiling point:: 251℃
Density: 1.923
Flash point:: 106℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: soluble in Methanol
form: powder to crystal
color: White to Almost white
Water Solubility: Slightly soluble in water (2.9 g/L) (25°C).
Sensitive: Lachrymatory

Less

Safety

Hazard Codes: C,T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN3261
HazardClass: 8
HS Code: 2916399090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5338
Product name: 3-Bromo-5-fluorobenzyl Bromide
Packaging: 5G
Price: $90
Updated: 2025/07/31

TCI Chemical

Product number: B5338
Product name: 3-Bromo-5-fluorobenzyl Bromide
Packaging: 25G
Price: $314
Updated: 2025/07/31

TRC

Product number: B961523
Product name: 3-Bromo-5-fluorobenzyl Bromide
Packaging: 10g
Price: $285
Updated: 2021/12/16

Apolloscientific

Product number: PC9276
Product name: 3-Bromo-5-fluorobenzyl Bromide
Purity: 98%
Packaging: 1g
Price: $29
Updated: 2021/12/16

SynQuest Laboratories

Product number: 1700-B-80
Product name: 3-Bromo-5-fluorobenzyl Bromide
Purity: 98%
Packaging: 1g
Price: $32
Updated: 2021/12/16

Less

3-Fluoro-5-bromobenzyl bromide Chemical Properties,Usage,Production

Uses

3-Bromo-5-fluorobenzyl bromide is employed as a intermediate for pharmaceutical and chemical research.

Synthesis

216755-56-5

216755-57-6

General procedure for the synthesis of 3-fluoro-5-bromobenzyl bromide from (3-bromo-5-fluorophenyl)methanol: 3-bromo-5-fluorobenzyl alcohol (1.79 g, 8.39 mmol) and triphenylphosphine (3.65 g, 10.10 mmol) were dissolved in dichloromethane (45 mL), followed by addition of carbon tetrabromide (3.34 g, 10.10 mmol). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the solvent was removed by vacuum evaporation. The residue was treated with diethyl ether (50 mL) and stirred at room temperature to form a white slurry. The slurry was filtered through CeliteTM and the residue was washed with diethyl ether (2 x 50 mL). The filtrate and washings were combined and the crude product was obtained by vacuum evaporation. The crude product was purified by silica gel column chromatography using 2% ethyl acetate/hexane as eluent to afford 3-bromo-5-fluorobenzyl bromide (2.21 g, 98%). The structure of the product was confirmed by 1H NMR, 19F NMR and 13C NMR.1H NMR (400 MHz, CDCl3): δ 7.33 (s, 1H), 7.18 (ddd, JHF 8.2 Hz, JHH = 2.0,2.0 Hz, 1H), 7.05 (ddd, JHF = 9.0 Hz, JHH = 1.8,1.6 Hz. 1H), 4.38 (s, 2H); 19F NMR (377 MHz, CDCl3): δ -110.19 to -110.14 (m, 1F); 13C NMR (101 MHz, CDCl3): δ 162.67 (d, JCF = 252.1 Hz), 141.61 (d, JCF = 8.5 Hz), 128.17 ( d, JCF = 3.1 Hz), 122.94 (d, JCF = 10.0 Hz), 119.39 (d, JCF = 24.6 Hz), 115.34 (d, JCF = 22.3 Hz), 31.31 (d, JCF = 2.3 Hz).

References

[1] Patent: WO2016/54728, 2016, A1. Location in patent: Paragraph 00128
[2] Patent: WO2016/74068, 2016, A1. Location in patent: Paragraph 00122
[3] Patent: CN104447730, 2017, B. Location in patent: Paragraph 0149-0150
[4] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 81
[5] Patent: US2002/49204, 2002, A1

3-Fluoro-5-bromobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3-Fluoro-5-bromobenzyl bromide Suppliers

Americas 1 China 106 Europe 1 India 4 Italy 1 Japan 1 Switzerland 1 United Kingdom 2 United States 11 Global 128

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1930
Advantage: 55

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD

Tel: 13816107857
Fax: qq: 276312098
Email: sales@fortunechem-sh.com
Country: China
ProdList: 984
Advantage: 58

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Shanghai Na Qian Chemical Technology Co. Ltd.

Tel: 13598610367
Fax: QQ:2468833170
Email: 2841375912@qq.com
Country: China
ProdList: 2788
Advantage: 52

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Nanjing XiLang Chemical Products Co., Ltd.

Tel: 18936048580
Email: chemxilang@163.com
Country: China
ProdList: 3909
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Hechemist Technology CO.,LTD

Tel: 18511709189
Fax: 010-58043593
Email: sales@hechemist.com
Country: China
ProdList: 2835
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Henan Anky Chemical Technology Co., Ltd.

Tel: 17836913271
Fax: 0374-8348899
Email: 3224305243@qq.com
Country: China
ProdList: 2944
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9856
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

TCI Chemicals

Tel: 021-67121386, 800-988-0390
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 5391
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8645
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9992
Advantage: 58

ChangShu HengYao Advanced Material Co.,Ltd.

Tel: 0510-15312278075 15312278075
Email: xxl_hotmail@163.com
Country: China
ProdList: 224
Advantage: 58

Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd.

Tel: 027-83855312 17771813295 13377865312
Email: 2668571332@qq.com
Country: China
ProdList: 1000
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-87569262 +86-15003564040
Fax: 029-88380327
Email: 1087@dideu.com
Country: China
ProdList: 3979
Advantage: 58

Richest Group Ltd

Tel: 18017061086
Email: oled@richest-group.com
Country: CHINA
ProdList: 5600
Advantage: 58

Less

View Lastest Price from 3-Fluoro-5-bromobenzyl bromide manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Fluoro-5-bromobenzyl bromide 216755-57-6
Price: US $0.00-0.00/KG
Min. Order: 10mg
Purity: 99%
Supply Ability: 2000tons
Release date: 2020-01-16

Hangzhou ICH Biofarm Co., Ltd

Product: 3-Fluoro-5-bromobenzyl bromide 216755-57-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2023-06-09

Career Henan Chemical Co

Product: 3-Fluoro-5-bromobenzyl bromide 216755-57-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-31

216755-57-6, 3-Fluoro-5-bromobenzyl bromideRelated Search:

2-Bromo-1-(bromomethyl)-4-fluorobenzene 3-BROMO-4-FLUOROBENZYL BROMIDE 2-Bromo-5-fluorobenzyl bromide 2-Chloro-4-fluorobenzyl bromide 2-Fluoro-6-bromobenzyl bromide 2-Fluoro-5-bromobenzyl bromide 2-Fluoro-4-chlorobenzyl bromide 3-CHLORO-4-FLUOROBENZYL BROMIDE 2-Chloro-5-fluorobenzyl bromide 3-Fluoro-4-bromobenzyl bromide 4-Bromo-2-fluorobenzyl bromide 2-Bromo-1-(bromomethyl)-3-fluorobenzene 5-BROMO-2,3-DIFLUOROBENZYL BROMIDE TETRABROMO-4-FLUORO-O-XYLENE 3-Fluoro-5-bromobenzyl bromide

3-Fluoro-5-bromobenzyl bromide

1-Bromo-3-(bromomethyl)-5-fluorobenzene

5-bromo-3-fluorobenzyl bromide

1-Bromo-3-(bromomethyl)-5-fluorobenzene, alpha,3-Dibromo-5-fluorotoluene

3-Fluoro-5-bromoben bromide

3-Fluoro-5-broMobenl broMide

3-Fluoride-5-Bromine Bromine Benzyl

Benzene, 1-bromo-3-(bromomethyl)-5-fluoro-

3-Bromo-5-fluorobenzylbromide,95%

216755-57-6

alkyl bromide| alkyl Fluorine

Fluorine series