Teicoplanin A2-5
- Product Name
- Teicoplanin A2-5
- CAS No.
- 91032-38-1
- Chemical Name
- Teicoplanin A2-5
- Synonyms
- teicoplanin A2-5;Teichomycin A2-5;Teicoplanin A2-5 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(9-methyl-1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
- CBNumber
- CB91215185
- Molecular Formula
- C89H99Cl2N9O33
- Formula Weight
- 1893.68
- MOL File
- 91032-38-1.mol
Teicoplanin A2-5 Property
- Density
- 1.67±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
- form
- lyophilisate
- pka
- 2.88±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- 20192
- Product name
- Teicoplanin A2-5
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $242
- Updated
- 2024/03/01
- Product number
- 20192
- Product name
- Teicoplanin A2-5
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $965
- Updated
- 2024/03/01
- Product number
- C4938
- Product name
- TeicoplaninA2-5
- Packaging
- 5mg
- Price
- $1104
- Updated
- 2021/12/16
- Product number
- 6172CX
- Product name
- TeicoplaninA2-5
- Packaging
- 5mg
- Price
- $1174
- Updated
- 2021/12/16
- Product number
- C4938
- Product name
- TeicoplaninA2-5
- Packaging
- 1mg
- Price
- $276
- Updated
- 2021/12/16
Teicoplanin A2-5 Chemical Properties,Usage,Production
Uses
Teicoplanin A2-5 is an antibiotic against Gram positive bacteria.
Uses
Teicoplanin A2-5 is the most non-polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis.
Definition
ChEBI: A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group.
Biological Activity
teicoplanin a2-5, derived from actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria.teicoplanin a2-5 is the most non-polar metabolite in the family of teicoplanins. teicoplanin, previously referred to in the literature as teichomycin, is a mixture of five closely related components of similar polarity, designated t-a2-1, 2, 3, 4 and 5 and of one more polar component, designated t-a3. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].
References
[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.
Teicoplanin A2-5 Preparation Products And Raw materials
Raw materials
Preparation Products
Teicoplanin A2-5 Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
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