1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)

Product Name: 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)
CAS No.: 190141-99-2
Chemical Name: 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)
Synonyms: 1-BOC-3-AMINO-4-HYDROXY-PYRROLIDINE;tert-Butyl 3-aMino-4-hydroxypyrrolidine-1-carboxylate;tert-Butyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate;2-Methyl-2-propanyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate;1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethyle...;3-Amino-4-hydroxy-1-pyrrolidinecarboxylic acid tert-butyl ester;tert-butyl 3-amino-4-hydroxy-pyrrolidine-1-carboxylate - [B84159];1-Pyrrolidinecarboxylic acid, 3-aMino-4-hydroxy-, 1,1-diMethylethyl ester;1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI);[trans-]-3-amino-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
CBNumber: CB91271716
Molecular Formula: C9H18N2O3
Formula Weight: 202.25
MOL File: 190141-99-2.mol

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1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) Property

Boiling point:: 309℃
Density: 1.179
Flash point:: 141℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 14.36±0.40(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C9H18N2O3/c1-9(2,3)14-8(13)11-4-6(10)7(12)5-11/h6-7,12H,4-5,10H2,1-3H3
InChIKey: MOZOQDNRVPHFOO-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CC(O)C(N)C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B814488
Product name: tert-Butyl3-amino-4-hydroxypyrrolidine-1-carboxylate
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144052
Product name: tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144052
Product name: tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
Packaging: 500mg
Price: $145
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144052
Product name: tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
Packaging: 1g
Price: $256
Updated: 2021/12/16

ChemScene

Product number: CS-0036146
Product name: tert-Butyl3-amino-4-hydroxypyrrolidine-1-carboxylate
Purity: >97.0%
Packaging: 5g
Price: $285
Updated: 2021/12/16

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1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) Chemical Properties,Usage,Production

Synthesis

114214-49-2

190141-99-2

The general procedure for the synthesis of tert-butyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate from 3-N-tert-butoxycarbonyl-6-oxa-3-azabicyclo[3.1.0]hexane is as follows: tert-butyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate (20 g, 0.11 mol) was mixed with ammonia (200 mL) and heated under reflux conditions to react Overnight. After completion of the reaction, the reaction mixture was concentrated in vacuum to afford the target product tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (21 g, 96% yield) as a light yellow oil.1H NMR (400 MHz, CDCl3) data were as follows: δ 3.98-3.97 (m, 1H), 3.75-3.61 (m, 2H), 3.36- 3.22 (m, 2H), 3.08-3.17 (m, 1H), 1.45 (s, 9H).

References

[1] Patent: WO2010/114971, 2010, A1. Location in patent: Page/Page column 153
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 3, p. 221 - 226
[3] Patent: WO2004/108661, 2004, A1. Location in patent: Page/Page column 48-49
[4] Patent: WO2005/28454, 2005, A1. Location in patent: Page/Page column 50-51
[5] Patent: WO2004/838, 2003, A1. Location in patent: Page 71

1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) Suppliers

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CHEMSTEP

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View Lastest Price from 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) 190141-99-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-10-04

190141-99-2, 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)Related Search:

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1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)

2-Methyl-2-propanyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate

3-Amino-4-Hydroxy-Pyrrolidine-1-Carboxylic Acid Tert-Butyl Ester(Mixture Of Cis&Trans)

1-BOC-3-AMINO-4-HYDROXY-PYRROLIDINE

tert-Butyl 3-aMino-4-hydroxypyrrolidine-1-carboxylate

1-Pyrrolidinecarboxylic acid, 3-aMino-4-hydroxy-, 1,1-diMethylethyl ester

3-Amino-4-hydroxy-1-pyrrolidinecarboxylic acid tert-butyl ester

tert-Butyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate

[trans-]-3-amino-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester

1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethyle...

tert-butyl 3-amino-4-hydroxy-pyrrolidine-1-carboxylate - [B84159]

190141-99-2

AMINOACID