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DONITRIPTAN

Product Name
DONITRIPTAN
CAS No.
170912-52-4
Chemical Name
DONITRIPTAN
Synonyms
DONITRIPTAN;DONITRIPTANUM;Donitriptan hydrochloride;Donitriptan, 10 mM in DMSO;4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile;Benzonitrile, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-;1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride;5-hydroxytryptamine Receptor,Donitriptan,Serotonin Receptor,Inhibitor,inhibit,5-HT Receptor
CBNumber
CB92451001
Molecular Formula
C23H25N5O2
Formula Weight
403.48
MOL File
170912-52-4.mol
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DONITRIPTAN Property

Boiling point:
727.1±60.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
Soluble in DMSO
pka
16.72±0.30(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
255184
Product name
Donitriptan hydrochloride
Packaging
10mg
Price
$409
Updated
2021/12/16
ChemScene
Product number
CS-0025002
Product name
Donitriptan
Packaging
25mg
Price
$550
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000403
Product name
DONITRIPTAN
Purity
95.00%
Packaging
10MG
Price
$721.59
Updated
2021/12/16
ChemScene
Product number
CS-0025002
Product name
Donitriptan
Packaging
50mg
Price
$900
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000403
Product name
DONITRIPTAN
Purity
95.00%
Packaging
50MG
Price
$1327.97
Updated
2021/12/16
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DONITRIPTAN Chemical Properties,Usage,Production

Uses

A novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine. An antimigraine agent.

Biological Activity

Brain penetrant 5-HT 1B/1D agonist (pK i values are 9.3 and 9.4 for 5-HT 1D and 5-HT 1B respectively). Inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. Displays antimigraine activity.

IC 50

5-HT1B Receptor: 9.4 (pKi); 5-HT1D Receptor: 9.3 (pKi)

DONITRIPTAN Preparation Products And Raw materials

Raw materials

Preparation Products

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DONITRIPTAN Suppliers

China 24 United Kingdom 1 United States 3 Global 28
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

170912-52-4, DONITRIPTANRelated Search:

DONITRIPTAN

  • DONITRIPTAN
  • 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride
  • Donitriptan hydrochloride
  • DONITRIPTANUM
  • 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile
  • Benzonitrile, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-
  • 5-hydroxytryptamine Receptor,Donitriptan,Serotonin Receptor,Inhibitor,inhibit,5-HT Receptor
  • Donitriptan, 10 mM in DMSO
  • 170912-52-4