ChemicalBook > CAS DataBase List > NEBULARINE

NEBULARINE

Product Name
NEBULARINE
CAS No.
550-33-4
Chemical Name
NEBULARINE
Synonyms
NSC65423;NEBULARINE;Purinosine;ribosylpurine;ribosyl-purin;PURINE RIBOSIDE;Ribosyl-isopurine;6-deaMinoadenosine;PURINE RIBONUCLEOSIDE;9-purineribonucleoside
CBNumber
CB9264951
Molecular Formula
C10H12N4O4
Formula Weight
252.23
MOL File
550-33-4.mol
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NEBULARINE Property

Melting point:
181-182°C
alpha 
D25 -48.6° (H2O)
Boiling point:
395.4°C (rough estimate)
Density 
1.3402 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Ethanol, Methanol (Slightly)
pka
13.13±0.70(Predicted)
form 
Solid
color 
Pale Beige to Beige
Merck 
13,6461
Stability:
Hygroscopic
InChI
InChI=1/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/s3
InChIKey
MRWXACSTFXYYMV-DOGWMMLDNA-N
SMILES
N1(C=NC2C=NC=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:9,10,12,14,r|
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RTECS 
UO9100000
Toxicity
LD50 in rats, guinea pigs (mg/kg): 220, 15 s.c. (Truant, D'Amato)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
N1240
Product name
Nebularine
Packaging
25MG
Price
$80
Updated
2025/07/31
TCI Chemical
Product number
N1240
Product name
Nebularine
Packaging
100MG
Price
$201
Updated
2025/07/31
Usbiological
Product number
207296
Product name
Nebularine
Packaging
500ug
Price
$325
Updated
2021/12/16
Usbiological
Product number
296421
Product name
Nebularine
Packaging
50mg
Price
$368
Updated
2021/12/16
Usbiological
Product number
N0570-70
Product name
Nebularine
Packaging
100mg
Price
$460
Updated
2021/12/16
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NEBULARINE Chemical Properties,Usage,Production

Description

This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).

Chemical Properties

Crystalline Solid

Uses

Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.

Definition

ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.

storage

+4°C

Purification Methods

Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]

NEBULARINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NEBULARINE Suppliers

Panaishen (Henan) Pharmaceutical Science and Technology Co. , Ltd.
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View Lastest Price from NEBULARINE manufacturers

Career Henan Chemical Co
Product
NEBULARINE 550-33-4
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 557
Release date
2019-09-01

550-33-4, NEBULARINERelated Search:


  • 9-(beta-d-ribofuranosyl)purine
  • 9-beta-d-ribofuranosyl-9h-purin
  • 9-beta-d-ribofuranosyl-9h-purine
  • 9-purineribonucleoside
  • ribosyl-purin
  • ribosylpurine
  • 1-(9H-Purine-9-yl)-1-deoxy-β-D-ribofuranose
  • 9-β-D-Ribofuranosyl-9H-purine
  • PURINE RIBONUCLEOSIDE
  • PURINE RIBOSIDE
  • PURINE 9BETA-D-RIBOFURANOSIDE
  • NEBULARINE
  • Purine-9-D-Ribofuranoside
  • 9H-Purine, 9-.beta.-D-ribofuranosyl-
  • NSC65423
  • Nebularine (high purity)
  • 9-beta-D-Ribosyl-9H-purine
  • Purinosine
  • Ribosyl-isopurine
  • 6-deaMinoadenosine
  • 9H-Purine, 9-β-D-ribofuranosyl-
  • 6-Deaminoadenosine, purine riboside, Nabularine
  • (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol
  • Nebularine,6-Deamino adenosine
  • Nebularine in methanol
  • 9--D-ribofuranosyl-9H-purine
  • 550-33-4
  • Sugars, Carbohydrates & Glucosides
  • Bases & Related Reagents
  • Nucleotides