ABP688

Product Name: ABP688
CAS No.: 924298-51-1
Chemical Name: ABP688
Synonyms: ABP688;ABP 924298-51-1;ABP688, 10 mM in DMSO;3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime;3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime;2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
CBNumber: CB92669578
Molecular Formula: C15H16N2O
Formula Weight: 240.3
MOL File: 924298-51-1.mol

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ABP688 Property

Boiling point:: 361.4±52.0 °C(Predicted)
Density: 1.03±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 100 mM
form: A solid
pka: 2.78±0.19(Predicted)
color: Light brown to brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 5229
Product name: ABP688
Purity: ≥98%(HPLC)
Packaging: 10
Price: $163
Updated: 2021/12/16

Tocris

Product number: 5229
Product name: ABP688
Purity: ≥98%(HPLC)
Packaging: 50
Price: $683
Updated: 2021/12/16

TRC

Product number: A106525
Product name: ABP688
Packaging: 50mg
Price: $580
Updated: 2021/12/16

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ABP688 Chemical Properties,Usage,Production

Uses

ABP 688 is a high affinity and selective of metabotropic glutamate receptor (mGluR5). Also, it inhibits glutamate induced calcium release from L(tk-) cells expressing human mGlu5 receptors.

Enzyme inhibitor

This high-affinity mGluR antagonist (FW = 240.31 g/mol; CAS 924298- 51-1; Soluble to 100 mM in DMSO; 50 mM in 1 eq. HCl), also named 3- [2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime, targets the human metabolotrophic glutamate receptor-5 (mGluR5) (Ki = 1.7 nM) and inhibits glutamate-induced calcium release from Ltk-cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Indeed, [11C]- ABP688 is a useful PET tracer for in vivo imaging of the mGluR5 in rodents.

IC 50

human mGluR5: 1.7 nM (Ki)

storage

Store at -20°C

ABP688 Preparation Products And Raw materials

Raw materials

Preparation Products

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ABP688 Suppliers

China 22 India 1 United Kingdom 1 United States 6 Global 30

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924298-51-1, ABP688Related Search:

ABP688

ABP 924298-51-1

3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime

2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime

3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime

ABP688, 10 mM in DMSO

924298-51-1