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ABP688

Product Name
ABP688
CAS No.
924298-51-1
Chemical Name
ABP688
Synonyms
ABP688;ABP 924298-51-1;ABP688, 10 mM in DMSO;3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime;3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime;2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
CBNumber
CB92669578
Molecular Formula
C15H16N2O
Formula Weight
240.3
MOL File
924298-51-1.mol
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ABP688 Property

Boiling point:
361.4±52.0 °C(Predicted)
Density 
1.03±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mM
form 
A solid
pka
2.78±0.19(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
5229
Product name
ABP688
Purity
≥98%(HPLC)
Packaging
10
Price
$163
Updated
2021/12/16
Tocris
Product number
5229
Product name
ABP688
Purity
≥98%(HPLC)
Packaging
50
Price
$683
Updated
2021/12/16
TRC
Product number
A106525
Product name
ABP688
Packaging
50mg
Price
$580
Updated
2021/12/16
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ABP688 Chemical Properties,Usage,Production

Uses

ABP 688 is a high affinity and selective of metabotropic glutamate receptor (mGluR5). Also, it inhibits glutamate induced calcium release from L(tk-) cells expressing human mGlu5 receptors.

Enzyme inhibitor

This high-affinity mGluR antagonist (FW = 240.31 g/mol; CAS 924298- 51-1; Soluble to 100 mM in DMSO; 50 mM in 1 eq. HCl), also named 3- [2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime, targets the human metabolotrophic glutamate receptor-5 (mGluR5) (Ki = 1.7 nM) and inhibits glutamate-induced calcium release from Ltk-cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Indeed, [11C]- ABP688 is a useful PET tracer for in vivo imaging of the mGluR5 in rodents.

IC 50

human mGluR5: 1.7 nM (Ki)

storage

Store at -20°C

ABP688 Preparation Products And Raw materials

Raw materials

Preparation Products

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ABP688 Suppliers

China 22 India 1 United Kingdom 1 United States 6 Global 30
BOC Sciences
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1-631-485-4226; 16314854226
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United States Biological
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924298-51-1, ABP688Related Search:


  • ABP688
  • ABP 924298-51-1
  • 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime
  • 2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
  • 3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime
  • ABP688, 10 mM in DMSO
  • 924298-51-1