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LENAMPICILLIN HYDROCHLORIDE

Product Name
LENAMPICILLIN HYDROCHLORIDE
CAS No.
80734-02-7
Chemical Name
LENAMPICILLIN HYDROCHLORIDE
Synonyms
kb1585;kbt1585;kbt-1585;varacillin;takacillin;LENAMPICILLIN;LenampicillinHCl;KBT-1585 HYDROCHLORIDE;Lempicillin hydrochloride;Lenanpicillin hydrochloride
CBNumber
CB9302877
Molecular Formula
C21H23N3O7S
Formula Weight
461.49
MOL File
80734-02-7.mol
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LENAMPICILLIN HYDROCHLORIDE Property

Melting point:
145° (dec)
storage temp. 
Store at -20°C, sealed storage, away from moisture and light
solubility 
DMSO:100.0(Max Conc. mg/mL);200.82(Max Conc. mM)
form 
Solid
color 
White to off-white
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Safety

Toxicity
LD50 in male, female rats, male, female mice (mg/kg): approx 10000, approx 10000, 8294, 8492 orally; 4362, 4471, 3576, 4284 s.c.; 876, 838, 711, 775 i.v.; in dogs (mg/kg): >300 orally (Ogino)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
L328100
Product name
LenampicillinHydrochloride
Packaging
10mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
281219
Product name
Lenampicillin hydrochloride
Packaging
5mg
Price
$460
Updated
2021/12/16
TRC
Product number
L328100
Product name
LenampicillinHydrochloride
Packaging
100mg
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0025153
Product name
LENAMPICILLIN HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$497.49
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
47096
Product name
LenampicillinHCl
Packaging
10mg
Price
$650
Updated
2021/12/16
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LENAMPICILLIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Lenampicillin is an oral ampicillin prodrug. Antibiotic used in the treatment of respiratory tract infections and urinary tract infections.

Definition

ChEBI: Valacillin (TN) is a peptide.

in vivo

Lenampicillin hydrochloride (KBT-1585) (oral adminstration; 0-1000 mg/kg) does not lead to death in dogs, and maximum dose of in this acute toxicity study is recorded because of causing emesis[2].Lenampicillin hydrochloride (LAPC) are identified for it main metabolites in rat and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dog, On the other hand, high levels of acetoin is found in portal plasma for early period after dosing of LAPC. These results shows that the biotransformation of promoiety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in liver[3].

LENAMPICILLIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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LENAMPICILLIN HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
Advantage
58

80734-02-7, LENAMPICILLIN HYDROCHLORIDERelated Search:


  • (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-d-alpha-aminobenzylpenicillinatehyd
  • -2-carboxylicacid,hydrochloride
  • -amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane
  • ampicillin,(5-methyl-2-oxo-1,3-dioxolen-4-yl)methylester,hydrochloride
  • carbonicacid,cyclic1-(hydroxymethyl)-2-methylethyleneester,esterwith6-(2
  • kb1585
  • kbt1585
  • kbt-1585
  • takacillin
  • varacillin
  • (2S,5R,6R)-6-[[(2R)-AMinophenylacetyl]aMino]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester Hydrochloride
  • [2S-[2α,5α,6β(S*)]]-6-[(AMinophenylacetyl)aMino]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester MonoHydrochloride
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, monohydrochloride, (2S,5R,6R)- (9CI)
  • Lenanpicillin hydrochloride
  • LENAMPICILLIN
  • LenampicillinHCl
  • LENAMPICILLIN HYDROCHLORIDE
  • Lenampicillin hydrochloride (KBT-1585 hydrochloride)
  • KBT-1585 HYDROCHLORIDE
  • Lempicillin hydrochloride
  • 80734-02-7
  • C21H23N3O7S
  • Amines
  • Drug Analogues
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds