SELENOUREA

SELENOUREA Property

Melting point:

210-215 °C (dec.)

Boiling point:

200°C (rough estimate)

storage temp. 

2-8°C

solubility 

DMSO (Slightly, Heated)

form 

solid

color 

pink

Water Solubility 

Soluble in water, alcohol and ether.

Sensitive 

Air & Moisture Sensitive

BRN 

1734744

Exposure limits

ACGIH: TWA 0.2 mg/m3
NIOSH: IDLH 1 mg/m3; TWA 0.2 mg/m3

InChI

InChI=1S/CH4N2Se/c2-1(3)4/h(H4,2,3,4)

InChIKey

IYKVLICPFCEZOF-UHFFFAOYSA-N

SMILES

NC(N)=[Se]

CAS DataBase Reference

630-10-4(CAS DataBase Reference)

EPA Substance Registry System

Selenourea (630-10-4)

Safety

Hazard Codes 

T,N

Risk Statements 

23/25-33-50/53

Safety Statements 

20/21-28-45-60-61

RIDADR 

UN 3283 6.1/PG 2

WGK Germany 

3

RTECS 

YU1820000

F 

8-10-23

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29310099

Hazardous Substances Data

630-10-4(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H331Toxic if inhaled

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

SELENOUREA Chemical Properties,Usage,Production

Chemical Properties

slightly pink to grey crystalline needles

Uses

Selenourea is used in the synthesis of selenium heterocycles, which exhibit anti-inflammatory and anti-tumor activity. It acts as an effective ligand and form complexes with transition metals and metalloids.

Definition

ChEBI: Selenourea is a member of ureas and a one-carbon compound. It is functionally related to a urea.

General Description

Solid.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NO, and Se. See also SELENIUM COMPOUNDS

Purification Methods

Recrystallise it from the least volume of H2O using Norite (preferably under N2) to form colourless needles which are dried over P2O5. It is air and light sensitive. It slowly turns moderately dark on storage even below 0o. [King & Hlavacek J Am Chem Soc 73 1864 1951, Dunbar & Painter J Am Chem Soc 69 1833 1947, Bacher & Bos Recl Trav Chim Pays Bas 62 580 1943, Hope Acta Chem Scand 18 1800 1964.] The Se-methyl iodide provides yellow crystals from EtOH/Et2O with m 187-188o(dec). The N,N-dimethyl derivative crystallises from H2O or EtOH as colourless needles which slowly turn pink, then gray on standing, and although slightly soluble in *benzene it can be recrystallised from it and has m 167-170o(dec) [Zingaro et al. J Org Chem 18 292 1953, IR: Jensen & Nielsen Acta Chem Scand 20 597 1966, Beilstein 3 IV 435.]