ChemicalBook > CAS DataBase List > LM22B-10

LM22B-10

Product Name
LM22B-10
CAS No.
342777-54-2
Chemical Name
LM22B-10
Synonyms
LM22B-10;2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol;Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-;2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL;inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases
CBNumber
CB93356163
Molecular Formula
C27H33ClN2O4
Formula Weight
485.01
MOL File
342777-54-2.mol
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LM22B-10 Property

Boiling point:
718.9±60.0 °C(Predicted)
Density 
1.287±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form 
A crystalline solid
pka
14.00±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2461
Product name
LM22B-10
Purity
≥98% (HPLC)
Packaging
5mg
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2461
Product name
LM22B-10
Purity
≥98% (HPLC)
Packaging
25mg
Price
$411
Updated
2024/03/01
Cayman Chemical
Product number
29037
Product name
LM22B-10
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
29037
Product name
LM22B-10
Packaging
25mg
Price
$365
Updated
2024/03/01
Cayman Chemical
Product number
29037
Product name
LM22B-10
Packaging
10mg
Price
$166
Updated
2024/03/01
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LM22B-10 Chemical Properties,Usage,Production

Uses

LM22B-10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant.

storage

Store at -20°C

LM22B-10 Preparation Products And Raw materials

Raw materials

Preparation Products

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LM22B-10 Suppliers

China 41 India 1 United Kingdom 1 United States 5 Global 48
Shanghai Lollane Biological Technology Co.,Ltd.
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ShangHai Biochempartner Co.,Ltd
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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Career Henan Chemica Co
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342777-54-2, LM22B-10Related Search:


  • LM22B-10
  • 2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL
  • 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
  • Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-
  • inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases
  • 342777-54-2