t-Boc-N-Amido-PEG7-Tos

Product Name: t-Boc-N-Amido-PEG7-Tos
CAS No.: 1292268-14-4
Chemical Name: t-Boc-N-Amido-PEG7-Tos
Synonyms: NHBoc-PEG7-Tos;Tos-PEG7-NH-Boc;Boc-NH-PEG7-Tos;t-Boc-N-Amido-PEG7-Tos;Boc-NH-PEG-7-Tos,inhibit,Inhibitor,BocNHPEG7Tos,PROTAC Linkers,Boc NH PEG7 Tos;2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
CBNumber: CB94849671
Molecular Formula: C26H45NO11S
Formula Weight: 579.7
MOL File: 1292268-14-4.mol

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t-Boc-N-Amido-PEG7-Tos Property

Boiling point:: 656.0±55.0 °C(Predicted)
Density: 1.155±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 12.23±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24109
Product name: t-Boc-N-Amido-PEG7-Tos
Purity: 98%
Packaging: 500mg
Price: $890
Updated: 2021/12/16

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t-Boc-N-Amido-PEG7-Tos Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG7-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.

Uses

Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG7-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-Amido-PEG7-Tos Suppliers

China 28 United States 1 Global 29

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View Lastest Price from t-Boc-N-Amido-PEG7-Tos manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: NHBoc-PEG7-Tos 1292268-14-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

1292268-14-4, t-Boc-N-Amido-PEG7-TosRelated Search:

t-Boc-N-Amido-PEG7-Tos

Boc-NH-PEG7-Tos

5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester

NHBoc-PEG7-Tos

Boc-NH-PEG-7-Tos,inhibit,Inhibitor,BocNHPEG7Tos,PROTAC Linkers,Boc NH PEG7 Tos

2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate

Tos-PEG7-NH-Boc

1292268-14-4

C26H45NO11S