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t-Boc-N-Amido-PEG7-Tos

Product Name
t-Boc-N-Amido-PEG7-Tos
CAS No.
1292268-14-4
Chemical Name
t-Boc-N-Amido-PEG7-Tos
Synonyms
NHBoc-PEG7-Tos;Tos-PEG7-NH-Boc;Boc-NH-PEG7-Tos;t-Boc-N-Amido-PEG7-Tos;Boc-NH-PEG-7-Tos,inhibit,Inhibitor,BocNHPEG7Tos,PROTAC Linkers,Boc NH PEG7 Tos;2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
CBNumber
CB94849671
Molecular Formula
C26H45NO11S
Formula Weight
579.7
MOL File
1292268-14-4.mol
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t-Boc-N-Amido-PEG7-Tos Property

Boiling point:
656.0±55.0 °C(Predicted)
Density 
1.155±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
pka
12.23±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24109
Product name
t-Boc-N-Amido-PEG7-Tos
Purity
98%
Packaging
500mg
Price
$890
Updated
2021/12/16
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t-Boc-N-Amido-PEG7-Tos Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG7-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.

Uses

Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG7-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-Amido-PEG7-Tos Suppliers

China 28 United States 1 Global 29
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
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View Lastest Price from t-Boc-N-Amido-PEG7-Tos manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
NHBoc-PEG7-Tos 1292268-14-4
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-25

1292268-14-4, t-Boc-N-Amido-PEG7-TosRelated Search:


  • t-Boc-N-Amido-PEG7-Tos
  • Boc-NH-PEG7-Tos
  • 5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
  • NHBoc-PEG7-Tos
  • Boc-NH-PEG-7-Tos,inhibit,Inhibitor,BocNHPEG7Tos,PROTAC Linkers,Boc NH PEG7 Tos
  • 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate
  • Tos-PEG7-NH-Boc
  • 1292268-14-4
  • C26H45NO11S