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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-

Product Name
Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
CAS No.
55040-82-9
Chemical Name
Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
Synonyms
WAY-605462;5-LOX-IN-1;(2-Morpholino-4-phenylthiazol-5-yl)(phenyl)methanone;Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
CBNumber
CB95968058
Molecular Formula
C20H18N2O2S
Formula Weight
350.43
MOL File
55040-82-9.mol
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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Property

storage temp. 
Store at -20°C
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Chemical Properties,Usage,Production

Description

IC50: 2.3 μM (5-LOX)[1]

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1].

Uses

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

References

[1] Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50. DOI:10.1016/j.ejmech.2018.08.098

Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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55040-82-9, Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-Related Search:


  • Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
  • WAY-605462
  • (2-Morpholino-4-phenylthiazol-5-yl)(phenyl)methanone
  • 5-LOX-IN-1
  • 55040-82-9