ChemicalBook > CAS DataBase List > Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
- Product Name
- Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
- CAS No.
- 55040-82-9
- Chemical Name
- Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
- Synonyms
- WAY-605462;5-LOX-IN-1;(2-Morpholino-4-phenylthiazol-5-yl)(phenyl)methanone;Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
- CBNumber
- CB95968058
- Molecular Formula
- C20H18N2O2S
- Formula Weight
- 350.43
- MOL File
- 55040-82-9.mol
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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Property
- storage temp.
- Store at -20°C
- form
- Solid
- color
- Light yellow to yellow
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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Chemical Properties,Usage,Production
Description
IC50: 2.3 μM (5-LOX)[1]
5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].
5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1].
Uses
5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].
References
[1] Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50. DOI:10.1016/j.ejmech.2018.08.098
Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Preparation Products And Raw materials
Raw materials
Preparation Products
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Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl- Suppliers
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