2-FLUORO-5-NITROPHENYLACETIC ACID
- Product Name
- 2-FLUORO-5-NITROPHENYLACETIC ACID
- CAS No.
- 195609-18-8
- Chemical Name
- 2-FLUORO-5-NITROPHENYLACETIC ACID
- Synonyms
- 2-FLUORO-5-NITROPHENYLACETIC;2-fluoro-5-nitrophenyl acetate;2-FLUORO-5-NITROPHENYLACETIC ACID;2-(2-fluoro-5-nitrophenyl)aceticaci;Benzeneacetic acid, 2-fluoro-5-nitro-;2-(2-Fluoro-5-nitrophenyl)acetic acid;3-(Carboxymethyl)-4-fluoronitrobenzene;2-FLUORO-5-NITROPHENYLACETIC ACID ISO 9001：2015 REACH
- CBNumber
- CB9730131
- Molecular Formula
- C8H6FNO4
- Formula Weight
- 199.14
- MOL File
- 195609-18-8.mol
2-FLUORO-5-NITROPHENYLACETIC ACID Property
- Melting point:
- 149-150
- Boiling point:
- 375.5±27.0 °C(Predicted)
- Density
- 1.498
- storage temp.
- Store at room temperature
- form
- powder
- pka
- 3.76±0.10(Predicted)
- color
- Off white to faint lemon
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- F622040
- Product name
- 2-Fluoro-5-nitrophenylaceticAcid
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- W4168
- Product name
- 2-Fluoro-5-nitrophenylaceticacid
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- PC7840
- Product name
- 2-Fluoro-5-nitrophenylaceticacid
- Packaging
- 25g
- Price
- $67
- Updated
- 2021/12/16
- Product number
- 4754-3-01
- Product name
- 2-Fluoro-5-nitrophenylacetic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- 024824
- Product name
- 2-Fluoro-5-nitrophenylacetic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
2-FLUORO-5-NITROPHENYLACETIC ACID Chemical Properties,Usage,Production
Chemical Properties
Light yellow crystalline
Uses
2-Fluoro-5-nitrophenylacetic acid can be used to prepare thickened heterocyclic compounds as protein kinase inhibitors.
Synthesis
451-82-1
195609-18-8
General procedure for the synthesis of 2-fluoro-5-nitrophenylacetic acid from o-fluorophenylacetic acid: o-fluorobenzoic acid (30.0 g, 0.19 mol) was dissolved in a mixed solution of concentrated sulfuric acid (50 mL) and water (10 mL). A mixed solution of fuming nitric acid (10 mL) and water (10 mL) was added slowly and dropwise at 0 °C. The reaction mixture was kept stirred at 0 °C for 30 min. Upon completion of the reaction, the resulting precipitate was collected by filtration and washed with cold water. Finally, the product was dried under vacuum to afford 2-(2-fluoro-5-nitrophenyl)acetic acid as a white solid (35.2 g, 91% yield).
References
[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 99
[2] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 15, p. 2229 - 2235
[3] Tetrahedron, 2000, vol. 56, # 50, p. 9809 - 9818
[4] Patent: US2006/30609, 2006, A1. Location in patent: Page/Page column 15
2-FLUORO-5-NITROPHENYLACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-FLUORO-5-NITROPHENYLACETIC ACID Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
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- Germany
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- Advantage
- 58
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- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
- Tel
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- contact@chemcollect.de
- Country
- Germany
- ProdList
- 6214
- Advantage
- 54
View Lastest Price from 2-FLUORO-5-NITROPHENYLACETIC ACID manufacturers
- Product
- 2-(cyclopentyloxy)benzoic acid 195609-18-8
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2025-05-12
- Product
- 2-(2-fluoro-5-nitrophenyl)acetic acid 195609-18-8
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2025-05-12
- Product
- 2-FLUORO-5-NITROPHENYLACETIC ACID 195609-18-8
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26