3-CHLOROBENZHYDROL
- Product Name
- 3-CHLOROBENZHYDROL
- CAS No.
- 63012-03-3
- Chemical Name
- 3-CHLOROBENZHYDROL
- Synonyms
- AURORA KA-7060;3-CHLOROBENZHYDROL;3-CHLORODIPHENYLMETHANOL;(3-CHLORO-PHENYL)-PHENYL-METHANOL;Benzenemethanol, 3-chloro-α-phenyl-;Benzenemethanol, 3-chloro-a-phenyl-
- CBNumber
- CB9744152
- Molecular Formula
- C13H11ClO
- Formula Weight
- 218.68
- MOL File
- 63012-03-3.mol
3-CHLOROBENZHYDROL Property
- Melting point:
- 40 °C
- Boiling point:
- 169°C/0.1mm
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 13.28±0.20(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 63012-03-3(CAS DataBase Reference)
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B405168
- Product name
- (3-Chlorophenyl)(phenyl)methanol
- Packaging
- 1g
- Price
- $310
- Updated
- 2021/12/16
- Product number
- 9560AB
- Product name
- (3-Chlorophenyl)(phenyl)methanol
- Packaging
- 5g
- Price
- $429
- Updated
- 2021/12/16
- Product number
- HCH0021690
- Product name
- 3-CHLOROBENZHYDROL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $757.97
- Updated
- 2021/12/16
- Product number
- 9560AB
- Product name
- (3-Chlorophenyl)(phenyl)methanol
- Packaging
- 10g
- Price
- $805
- Updated
- 2021/12/16
- Product number
- NV00648
- Product name
- 3-CHLOROBENZHYDROL
- Packaging
- 1g
- Price
- $809
- Updated
- 2021/12/16
3-CHLOROBENZHYDROL Chemical Properties,Usage,Production
Uses
(3-Chlorophenyl)(phenyl)methanol is useful as T cell activators to treat viral infections and proliferative disorders, such as cancer.
Synthesis
1016-78-0
63012-03-3
General procedure for the synthesis of 3-chlorodiphenylmethanol from 3-chlorobenzophenone: (1) To a mixed solution of ethanol (100 mL) and tetrahydrofuran (THF, 100 mL) of 3-chlorobenzophenone (10.0 g, 46.2 mmol), sodium borohydride (876 mg, 23.1 mmol) was slowly added at room temperature. The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was poured into water and extracted with ethyl acetate. The organic phases were combined, washed with water and then dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to give 3-chlorodiphenylmethanol as a colorless oil in a yield of 9.53 g (94.4% yield). 1H-NMR (CDCl3) δ: 2.55 (1H, d, J = 3.6 Hz), 5.80 (1H, d, J = 3.6 Hz), 7.25 to 7.40 (9H, m).
References
[1] Organic Letters, 2000, vol. 2, # 5, p. 659 - 661
[2] Patent: EP1437344, 2004, A1. Location in patent: Page 48
[3] Recueil des Travaux Chimiques des Pays-Bas, 1912, vol. 31, p. 311
[4] Recueil des Travaux Chimiques des Pays-Bas, 1915, vol. 34, p. 162
[5] Recueil des Travaux Chimiques des Pays-Bas, 1919, vol. 38, p. 121
3-CHLOROBENZHYDROL Preparation Products And Raw materials
Raw materials
Preparation Products
3-CHLOROBENZHYDROL Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 0319-5801333-8008 15630992918
- sales@summedchem.com
- Country
- China
- ProdList
- 965
- Advantage
- 58
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9923
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0411-0411-00000000 13644282108
- Fax
- -
- 3500508746@qq.com
- Country
- China
- ProdList
- 2896
- Advantage
- 55
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58