1-(1H-INDAZOL-3-YL)ETHANONE

Product Name: 1-(1H-INDAZOL-3-YL)ETHANONE
CAS No.: 4498-72-0
Chemical Name: 1-(1H-INDAZOL-3-YL)ETHANONE
Synonyms: 3-ACETYLINDAZOLE;3-Acetyl-1H-indazole;3-Acetylindazole(WX626026);1-(indazol-3-yl)ethan-1-one;1-(1H-INDAZOL-3-YL)ETHANONE;1-(1H-Indazole-3-yl)ethanone;1-(1H-indazol-3-yl)ethan-1-one;Ethanone, 1-(1H-indazol-3-yl)-;Ethanone, 1-(1H-indazol-3-yl)- (9CI)
CBNumber: CB9748822
Molecular Formula: C9H8N2O
Formula Weight: 160.17
MOL File: 4498-72-0.mol

More

Less

1-(1H-INDAZOL-3-YL)ETHANONE Property

Melting point:: 182 °C
Boiling point:: 348.8±15.0 °C(Predicted)
Density: 1.264±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.87±0.40(Predicted)
Appearance: Off-white to light yellow Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

TRC

Product number: I655633
Product name: 1-(1H-Indazol-3-yl)ethanone
Packaging: 500mg
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: W6353
Product name: 1-(1H-Indazol-3-yl)ethanone
Packaging: 100mg
Price: $97
Updated: 2021/12/16

Matrix Scientific

Product number: 126431
Product name: 1-(1H-Indazol-3-yl)ethanone
Purity: >95%
Packaging: 1g
Price: $432
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0016505
Product name: 1-(1H-INDAZOL-3-YL)-ETHANONE
Purity: 95.00%
Packaging: 1G
Price: $727.65
Updated: 2021/12/16

Matrix Scientific

Product number: 126431
Product name: 1-(1H-Indazol-3-yl)ethanone
Purity: >95%
Packaging: 5g
Price: $1296
Updated: 2021/12/16

More

Less

1-(1H-INDAZOL-3-YL)ETHANONE Chemical Properties,Usage,Production

Synthesis Reference(s)

Synthesis, p. 937, 1992 DOI: 10.1055/s-1992-26268

Synthesis

351457-12-0

75-16-1

4498-72-0

GENERAL STEPS: To an anhydrous THF solution of N-methoxy-N-methyl-1H-indazole-3-carboxamide (950 mg, 4.63 mmol, 1.1 eq.), the mixture was cooled to 0 °C. Methylmagnesium bromide (7.7 mL, 23.17 mmol, 5.0 eq.) was slowly added dropwise at 0 °C. After the dropwise addition, the reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of NH4Cl solution (5 mL). Subsequently, the solvent was removed by distillation under reduced pressure and the obtained residue was purified by column chromatography (eluent: ethyl acetate/petroleum ether = 1/2) to afford 1-(1H-indazol-3-yl)ethanone (610 mg, 82.3% yield) as a yellow solid.

References

[1] Tetrahedron, 2007, vol. 63, # 2, p. 419 - 428
[2] Patent: WO2018/15818, 2018, A2. Location in patent: Paragraph 00237
[3] Patent: WO2018/64135, 2018, A1. Location in patent: Paragraph 0275-0278
[4] Patent: US2011/65700, 2011, A1. Location in patent: Page/Page column 17
[5] European Journal of Medicinal Chemistry, 2011, vol. 46, # 10, p. 5138 - 5145

1-(1H-INDAZOL-3-YL)ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(1H-INDAZOL-3-YL)ETHANONE Suppliers

China 71 Europe 1 India 1 United States 8 Global 81

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
Fax: +86 10 61256049
Email: sales@zeroschem.com
Country: China
ProdList: 1370
Advantage: 59

Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

More

Less

View Lastest Price from 1-(1H-INDAZOL-3-YL)ETHANONE manufacturers

Career Henan Chemical Co

Product: 1-(1H-INDAZOL-3-YL)ETHANONE 4498-72-0
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 200kg
Release date: 2020-03-06

4498-72-0, 1-(1H-INDAZOL-3-YL)ETHANONERelated Search:

4-Fluoro-1-methylindazole 5-BROMO-3-HYDROXY (1H)INDAZOLE 1H-Indazole-7-carboxamide(9CI) 3-BROMO-4-FLUORO (1H)INDAZOLE 1-METHYL-5-NITRO-1H-INDAZOLE 6-Bromo-1H-indazol-3-ol 3-(1H-INDAZOL-3-YL)-3-OXO-PROPIONIC ACID ETHYL ESTER 1-(1H-INDAZOL-3-YL)ETHANONE 1-(6-METHOXY-1H-INDAZOL-3-YL)-ETHANONE CHEMPACIFIC 39982 1-(6-METHOXY-1H-INDAZOL-3-YL)-2-METHYLPROPAN-1-ONE 1-(6-METHOXY-1H-INDAZOL-3-YL)-PROPAN-1-ONE 1H-INDAZOLE-3-YLPHENYL METHANONE (6-METHOXY-1H-INDAZOL-3-YL)(PHENYL)METHANONE 3-BENZOYL-1-METHYL-1H-NAPHTHO[2,3-G]INDAZOLE-6,11-DIONE 3-BENZOYL-1H-NAPHTHO[2,3-G]INDAZOLE-6,11-DIONE 3-(2-OXO-2-PHENYLACETYL)-1H-NAPHTHO[2,3-G]INDAZOLE-6,11-DIONE SINOVA SL-02763

1-(1H-INDAZOL-3-YL)ETHANONE

Ethanone, 1-(1H-indazol-3-yl)- (9CI)

3-ACETYLINDAZOLE

1-(1H-Indazole-3-yl)ethanone

3-Acetyl-1H-indazole

1-(indazol-3-yl)ethan-1-one

Ethanone, 1-(1H-indazol-3-yl)-

3-Acetylindazole(WX626026)

1-(1H-indazol-3-yl)ethan-1-one

4498-72-0

ACETYLGROUP