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DC-CHOL

Product Name
DC-CHOL
CAS No.
166023-21-8
Chemical Name
DC-CHOL
Synonyms
DC-CHO;DC-CHOL;DC-CHOLESTEROL;DC-Cholesterol.HCl;DC-Chol (hydrochloride);DC-cholesterol hydrochloride;Cholesteryl 3β-N-(dimethylaminoethyl)carbamate;cholesteryl 3B-(N-(dimethylaminoethyl)*carbamate);3β-[n-(dimethylaminoethane) carbamoyl] cholesterol;Cholesteryl 3β-N-(di-methyl-amino-ethyl)-carbamate
CBNumber
CB9751215
Molecular Formula
C32H56N2O2.ClH
Formula Weight
537.26
MOL File
166023-21-8.mol
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DC-CHOL Property

storage temp. 
-20°C
solubility 
DMSO: > 5mg/mL; Methanol: > 10 mg/mL
form 
A crystalline solid
color 
White to light yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C2832
Product name
Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride
Purity
≥95%
Packaging
25mg
Price
$123
Updated
2024/03/01
Sigma-Aldrich
Product number
C2832
Product name
Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride
Purity
≥95%
Packaging
100mg
Price
$240
Updated
2024/03/01
Cayman Chemical
Product number
16943
Product name
DC-Chol (hydrochloride)
Packaging
50mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
16943
Product name
DC-Chol (hydrochloride)
Packaging
250mg
Price
$486
Updated
2024/03/01
Cayman Chemical
Product number
16943
Product name
DC-Chol (hydrochloride)
Packaging
25mg
Price
$63
Updated
2024/03/01
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DC-CHOL Chemical Properties,Usage,Production

Description

DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE , has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.

Uses

This cationic cholesterol derivative forms liposomes with L-α-phosphatidylethanolamine, dioleoyl, that efficiently transfect mammalian cell lines.

Uses

DC-Cholesterol HCl is suitable:

  • for the preparation of ultrasound cationic microbubbles
  • to prepare liposomes
  • for the preparation of L-glutathione (GSH), loaded proliposomes

General Description

DC-Cholesterol HCl is a sterol-based transfection reagent.

Biochem/physiol Actions

DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).

storage

Store at -20°C

DC-CHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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DC-CHOL Suppliers

China 47 South Korea 1 Switzerland 1 United States 8 Global 57
Adamas Reagent, Ltd.
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Chemsky（shanghai）International Co.,Ltd.
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ShenZhen InnoSyn Biotech Co.,Ltd
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Shanghai Macklin Biochemical Co.,Ltd.
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Shanghai AECOM Biotechnology Co. , Ltd.
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Sigma-Aldrich
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Shochem(Shanghai)Co.,Ltd
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HUNAN CHEMFISH SCIENTIFIC CO.,LTD
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DC Chemicals
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Energy Chemical
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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TargetMol Chemicals Inc.
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RD International Technology Co., Limited
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SHANGHAI ZZBIO CO., LTD.
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
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XIAMEN SINOPEG BIOTECH CO., LTD.
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Shanghai Acmec Biochemical Technology Co., Ltd.
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Shanghai Yubo Biotechnology Co., Ltd.
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View Lastest Price from DC-CHOL manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
DC-Chol
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle , 10g/bottle, 100g/bottle
Release date
2024-07-30

166023-21-8, DC-CHOLRelated Search:

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  • cholesteryl 3B-(N-(dimethylaminoethyl)*carbamate)
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  • Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride|||DC-Chol (hydrochloride)|||DC-Cholesterol hydrochloride|||?Cholesteryl 3β-N-(dimethylaminoethyl)carbamate
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  • 166023-21-8
  • C32H56N2O2HCl
  • C32H57ClN2O2
  • C32H57N2O2Cl
  • C32H56N2O2
  • BioChemical
  • Transfection & Transformation
  • Molecular Biology
  • Cloning and Expression