ChemicalBook > CAS DataBase List > Gatipotuzumab
Gatipotuzumab
- Product Name
- Gatipotuzumab
- CAS No.
- 1264737-26-9
- Chemical Name
- Gatipotuzumab
- Synonyms
- Gatipotuzumab;Gatipotuzumab (anti-MUC1);Research Grade Gatipotuzumab;Research Grade Gatipotuzumab (DHD14201)
- CBNumber
- CB98081039
- Formula Weight
- 0
- MOL File
- Mol file
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Gatipotuzumab Property
- form
- Liquid
- color
- Colorless to light yellow
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Gatipotuzumab Chemical Properties,Usage,Production
Uses
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC)[1][2].
References
[1] Macchini M, et al. Results from the primary analysis of a 30 patient extension of the GATTO study, a phase Ib study combining the anti-MUC1 gatipotuzumab (GAT) with the anti-EGFR tomuzotuximab (TO) or panitumumab in patients with refractory solid tumors. European Journal of Cancer, 2020, 138: S5-S6.
[2] Danielczyk A, et al. PankoMab: a potent new generation anti-tumour MUC1 antibody. Cancer Immunol Immunother. 2006 Nov;55(11):1337-47. DOI:10.1007/s00262-006-0135-9
Gatipotuzumab Preparation Products And Raw materials
Raw materials
Preparation Products
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