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PTZ-343

Basic information Safety Supplier Related

PTZ-343 Basic information

Product Name:
PTZ-343
Synonyms:
  • 10H-Phenothiazine-10-propanesulfonic acid, sodiuM salt (1:1)
  • 10H-Phenothiazine-10-propanesulfonic acid sodium salt
  • Sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate
  • sodiuM 3-(phenothiazin-10-yl)propane-1-sulfonate
  • 3-(phenothiazin-10-yl)propane-1-sulfonate
  • PTZ-343
  • phenothiazine sodium salt
  • sodiuM 3-(phenothiazin-10-yl)pro
CAS:
101199-38-6
MF:
C15H16NNaO3S2
MW:
345.41
EINECS:
1592732-453-0
Mol File:
101199-38-6.mol
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PTZ-343 Chemical Properties

Melting point:
>232°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
InChI
InChI=1S/C15H15NO3S2.Na.H/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;;/h1-4,6-9H,5,10-11H2,(H,17,18,19);;
InChIKey
LAXVHQHEZUKIAE-UHFFFAOYSA-N
SMILES
C(N1C2=CC=CC=C2SC2C=CC=CC1=2)CCS(O)(=O)=O.[NaH]
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PTZ-343 Usage And Synthesis

Description

PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.

Uses

Sodium 3-?(10H-?Phenothiazin-?10-?yl)?propane-?1-?sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum.

in vitro

PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission.

PTZ-343 Preparation Products And Raw materials

Raw materials

PTZ-343Supplier

Henan Alpha Chemical Co., Ltd. Gold
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