N-(tert-Butyl)benzylamine Chemical Properties

Melting point:

-25 °C

Boiling point:

80 °C5 mm Hg(lit.)

Density 

0.881 g/mL at 25 °C(lit.)

vapor pressure 

12.1Pa at 25℃

refractive index 

n20/D 1.497(lit.)

Flash point:

176 °F

storage temp. 

Store below +30°C.

solubility 

2g/l

pka

9.77±0.29(Predicted)

form 

Oil

color 

Colourless

Water Solubility 

2 g/L (20 ºC)

Sensitive 

Air Sensitive

BRN 

507464

Dielectric constant

3.2400000000000002

InChIKey

DLSOILHAKCBARI-UHFFFAOYSA-N

LogP

2.9 at 25℃

CAS DataBase Reference

3378-72-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzenemethanamine, N-(1,1-dimethylethyl)-(3378-72-1)

EPA Substance Registry System

Benzenemethanamine, N-(1,1-dimethylethyl)- (3378-72-1)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-22-36/37/38

Safety Statements 

23-24/25-36-26-45-36/37/39

RIDADR 

2735

WGK Germany 

3

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29214980

MSDS

• Language:English Provider:N-(tert-Butyl)benzylamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-(tert-Butyl)benzylamine Usage And Synthesis

Preparation

N-(tert-Butyl)benzylamine can be prepared by refluxing condensation of tert-butylamine and benzyl chloride in dimethylformamide.

Chemical Properties

CLEAR COLOURLESS TO PALE YELLOW LIQUID

Uses

N-Benzyl-tert-butylamine, is used as a protected amine. It aids in the oxidation to the corresponding hydroxylamine and nitrone.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 9555, 1995 DOI: 10.1016/0040-4039(95)02046-2

Purification Methods

Dissolve the amine in Et2O, dry it over KOH pellets, filter and fractionate it in a N2 atmosphere to avoid reaction with CO2 from the air. The hydrochloride has m 245-246o(dec) (from MeOH/Me2CO) and the perchlorate has m 200-201o. [Freidfelder et al. J Am Chem Soc 80 4320 1958, Beilstein 12 IV 2166.]

N-(tert-Butyl)benzylamine(3378-72-1)Related Product Information

• tert-Butanol
• tert-Butylbenzene
• BENZYL GLYCIDYL ETHER
• 4-tert-Butylphenol
• Benzyltriethylammonium chloride
• Butyl acetate
• 4-tert-Butylcatechol
• 2-tert-Butylphenol
• Dibenzylideneacetone
• tert-Butyl methyl ether
• Methyl 4-tert-butylbenzoate
• 4-tert-Butylbenzylamine
• tert-Butyl hydroperoxide
• Benzyl bromide
• Benzyltrimethylammonium chloride
• Cyhalofop-butyl
• N,N-Dimethylbenzylamine
• tert-Butyldimethylsilyl chloride