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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride

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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Basic information

Product Name:
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
Synonyms:
  • 4-(4-Methylpiperizinomethyl)benzoylchloride2HCl
  • 4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride
  • 4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE
  • 4-[(4-Methyl-1-piperazinyl)methyl]benzoyl chloride dihydrochloride
  • 4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride
  • Benzoyl chloride,4-[(4-Methyl-1-piperazinyl)Methyl]-, hydrochloride (1:2)
  • 4‐[(4‐Methyl‐1‐piperazinyl)‐methyl]‐benzoyl chloride hydrochloride
  • 4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl
CAS:
106261-64-7
MF:
C13H18Cl2N2O
MW:
289.2
EINECS:
680-808-3
Mol File:
106261-64-7.mol
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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Chemical Properties

Melting point:
>240°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
100vol% at 20℃[vol%]
Stability:
Hygroscopic, Moisture Sensitive
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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Usage And Synthesis

Uses

4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochlorideSupplier

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