Basic information Safety Supplier Related

Minalrestat

Basic information Safety Supplier Related

Minalrestat Basic information

Product Name:
Minalrestat
Synonyms:
  • 2-(4-Bromo-2-fluorobenzyl)-6-fluoro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetraone
  • Unii-G44pe6qb31
  • Minalrestat
  • Spiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-
  • ARI509
  • ARI-509
  • WAY-ARI-509
  • WAYARI-509
CAS:
129688-50-2
MF:
C19H11BrF2N2O4
MW:
449.206
Mol File:
129688-50-2.mol
More
Less

Minalrestat Chemical Properties

Melting point:
231-232℃
Density 
1.45
More
Less

Minalrestat Usage And Synthesis

Uses

Inhibitor(aldose reductase).

Definition

ChEBI: Minalrestat is a member of isoquinolines.

in vivo

Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats[1].
Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats[2].

Animal Model:Alloxan (40 mg/kg i.v.)-induced diabetic rats[1]
Dosage:10 mg/kg/day
Administration:Oral gavage, for 30 days.
Result:Restored the decreased microvascular reactivity.

MinalrestatSupplier

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 18100677375
Email
sales@szzxbio.com
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
More
Less

Minalrestat(129688-50-2)Related Product Information