Tolmesoxide
Tolmesoxide Basic information
- Product Name:
- Tolmesoxide
- Synonyms:
-
- Tolmesoxide
- 4,5-Dimethoxy-2-(methylsulfinyl)toluene
- Benzene, 1,2-dimethoxy-4-methyl-5-(methylsulfinyl)-
- CAS:
- 38452-29-8
- MF:
- C10H14O3S
- MW:
- 214.28
- Mol File:
- 38452-29-8.mol
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Tolmesoxide Chemical Properties
- Boiling point:
- 364.0±42.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
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Tolmesoxide Usage And Synthesis
Uses
Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina[1].
References
[1] Collier J G, et al. Comparison of effects of tolmesoxide (RX71107), diazoxide, hydrallazine, prazosin, glyceryl trinitrate and sodium nitroprusside on forearm arteries and dorsal hand veins of man[J]. British journal of clinical pharmacology, 1978, 5(1): 35. DOI:10.1111/j.1365-2125.1978.tb01595.x