Basic information Safety Supplier Related

Qingyangshengenin B

Basic information Safety Supplier Related

Qingyangshengenin B Basic information

Product Name:
Qingyangshengenin B
Synonyms:
  • Qingyangshengenin B
  • Otophylloside B
  • Wilfoside C3N
  • qyc5
  • Pregn-5-en-20-one, 3-[(O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-12-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-8,14,17-trihydroxy-, (3β,12β,14β,17α)-
CAS:
106758-54-7
MF:
C49H78O16
MW:
923.15
Product Categories:
  • Steroids
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
106758-54-7.mol
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Qingyangshengenin B Chemical Properties

Boiling point:
898.5±65.0 °C(Predicted)
Density 
1.26±0.1 g/cm3 (20 ºC 760 Torr)
pka
11.92±0.70(Predicted)
form 
Solid
color 
White to off-white
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Qingyangshengenin B Usage And Synthesis

Chemical Properties

White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Qingyang ginseng and Artemisia annua.

Uses

Qingyang ginseng aglycone B has the functions of calming the liver and tonifying the kidney, removing phlegm and relieving spasm.

Definition

ChEBI: Otophylloside B is a steroid saponin that is 17alpha-pregnenolone which is substituted by hydroxy groups at positions 8, 12beta, 14beta and 17beta, in which the 14beta-hydrocy group has been acylated by formal condensation with the carboxy group of (2E)-3,4-dimethylpent-2-enoic acid, and in which the hydroxy group at position 3 has been glycosylated with 2,6-dideoxy-3-O-methyl-beta-D-arabino-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranos. A C-21 steroidal glycoside, it is the essential active ingredient of the traditional Chinese medicine Qingyangshen, isolated from Cynanchum otophyllum and used to treat epilepsy and rheumatic pain. It has a role as a plant metabolite and an anticonvulsant. It is an 8-hydroxy steroid, a 14beta-hydroxy steroid, a 17beta-hydroxy steroid, a steroid saponin, a trisaccharide derivative and a tertiary alpha-hydroxy ketone.

Biological Activity

Qingyangshengenin B C-21 steroidal glycoside isolated from Qingyangshen. It has a protective effect on Aβ toxicity and reduces Aβ deposition by reducing Aβ expression at the mRNA level. It has antiepileptic activity.

Qingyangshengenin BSupplier

Dalian Meilun Biotech Co., Ltd.
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BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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Chengdu Climax Biotech Co., Ltd.
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028-83311324 1278112614
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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