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NADP, Disodium Salt

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NADP, Disodium Salt Basic information

Product Name:
NADP, Disodium Salt
Synonyms:
  • COENZYME II
  • B-NICOTINAMIDE ADENINE DINUCLEOTIDE 3'-PHOSPHATE, DISODIUM SALT
  • BETA-NADP DISODIUM SALT
  • BETA-NADP-NA2
  • BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DISODIUM SALT
  • NADP, DISODIUM SALT
  • NADP+, DISODIUM SALT
  • NADP, NA2
CAS:
24292-60-2
MF:
C21H29N7NaO17P3
MW:
767.41
EINECS:
246-129-8
Product Categories:
  • Bioproducts
  • Cofactor
Mol File:
24292-60-2.mol
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NADP, Disodium Salt Chemical Properties

Melting point:
175-178 °C
Density 
1.66g/cm3 at 20℃
vapor pressure 
0.002-0.004Pa at 20-25℃
storage temp. 
-20°C
solubility 
DMSO (Slightly), Water (Slightly)
form 
Powder
color 
Yellow
PH
4.0 ± 1.0(10mg/mL)
Odor
Odorless
Water Solubility 
>50 g/L
Stability:
Hygroscopic
InChIKey
UNRRSQIQTVFDLS-WUEGHLCSSA-L
LogP
-4.4 at 20℃ and pH7
Surface tension
73.2mN/m at 1g/L and 20℃
CAS DataBase Reference
24292-60-2
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-36-26
WGK Germany 
3
10-21
HS Code 
29349990

MSDS

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NADP, Disodium Salt Usage And Synthesis

Description

NADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. Prepared in large quantities.

Chemical Properties

Yellowish powder

Uses

Disodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.

Uses

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.

Application

A participant coenzyme in aerobic and anaerobic oxidation
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.

General Description

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.

Mechanism of action

β-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.

Biotechnological Applications

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.

Precautions

Protect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.

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