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Lisinopril R,S,S-Diketopiperazine

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Lisinopril R,S,S-Diketopiperazine Basic information

Product Name:
Lisinopril R,S,S-Diketopiperazine
Synonyms:
  • (2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-phenylbutanoic Acid
  • (2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-α]pyrazin-2(1H)-yl]-4-phenylbutanoic Acid
  • Pyrrolo[1,2-a]pyrazine-2(1H)-acetic acid, 3-(4-aMinobutyl)hexahydro-1,4-dioxo-a-(2-phenylethyl)-, (aS,3S,8aR)-
  • Lisinopril EP IMpurity D
  • Lisinopril Impurity 4(Lisinopril EP Impurity D)
  • Lisinopril-EP-Imp-D
  • Lisinopril impurity 3/Lisinopril EP Impurity D/R,S,S-Diketopiperazine
  • (2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1
CAS:
219677-82-4
MF:
C21H29N3O4
MW:
387.47
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Various Metabolites and Impurities
  • Pharmaceuticals
Mol File:
219677-82-4.mol
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Lisinopril R,S,S-Diketopiperazine Chemical Properties

Melting point:
>214oC (dec.)
Boiling point:
650.8±55.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka
3.56±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Lisinopril R,S,S-Diketopiperazine Usage And Synthesis

Uses

Lisinopril impurity

Uses

Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).

Definition

ChEBI: Lisinopril (8r,s)-diketopiperazine is a dipeptide.

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