Cidofovir Chemical Properties

Melting point:

>250°C (dec.)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO (Sparingly), Water (Sparingly)

form 

Solid

color 

White

InChI

InChI=1/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/s3

InChIKey

VWFCHDSQECPREK-ISZMHOAENA-N

SMILES

N1C(=O)N(C[C@@H](CO)OCP(O)(=O)O)C=CC=1N |&1:5,r|

Safety Information

HS Code 

2933599550

Cidofovir Usage And Synthesis

Chemical Properties

White Solid

Uses

An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefo re prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV).

Uses

Cidofovir Dihydrate is used in treatment of pain and combination with analgesics.

Definition

ChEBI: The dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

brand name

Vistide (Gilead Sciences).