Lintopride
Lintopride Basic information
- Product Name:
- Lintopride
- Synonyms:
-
- Lintopride
- Benzamide, 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydro-1H-imidazol-2-yl)methyl]-2-methoxy-
- CAS:
- 107429-63-0
- MF:
- C14H19ClN4O2
- MW:
- 310.78
- Mol File:
- 107429-63-0.mol
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Lintopride Chemical Properties
- Boiling point:
- 494.1±45.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 13.20±0.46(Predicted)
- color
- Light yellow to yellow
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Lintopride Usage And Synthesis
Biological Activity
Lintopride is a 5HT4 antagonist with a slight antagonistic effect on 5HT3.
in vitro
Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride.
target
| 5-HT 4 Receptor
| 5-HT 3 Receptor
|
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