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Ethyl indole-3-carboxylate

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Ethyl indole-3-carboxylate Basic information

Product Name:
Ethyl indole-3-carboxylate
Synonyms:
  • 1H-INDOLE-3-CARBOXYLIC ACID ETHYL ESTER
  • ETHYL INDOLE-3-CARBOXYLATE
  • INDOLE-3-CARBOXYLIC ACID ETHYL ESTER
  • 3-CARBETHOXYINDOLE
  • RARECHEM AL BI 0095
  • SPECS AN-068/14539028
  • INDOLE-3-CARBOXYLIC ACID ETHYL ESTER(I3CAEt)
  • 3-(Ethoxycarbonyl)indole
CAS:
776-41-0
MF:
C11H11NO2
MW:
189.21
EINECS:
805-824-1
Product Categories:
  • IndoleDerivative
  • Indole
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
Mol File:
776-41-0.mol
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Ethyl indole-3-carboxylate Chemical Properties

Melting point:
120-124 °C
Boiling point:
342.4±15.0 °C(Predicted)
Density 
1.210±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
15.42±0.30(Predicted)
color 
Light yellow to Brown
CAS DataBase Reference
776-41-0(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
2933998090
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Ethyl indole-3-carboxylate Usage And Synthesis

Chemical Properties

Yellow solid

Uses

Ethyl Indole-3-carboxylate is a compound that has been isolated from the south China sea sponge, Xetospongia testudinaria.

Uses

Reactant for preparation of:

  • Indole-based heterocycles for synthesis of indole-based p38 inhibitors and gramines
  • Glycine receptor ligands
  • Inhibitors of Human 5-Lipoxygenase
  • Antimicrobial agents

Synthesis Reference(s)

The Journal of Organic Chemistry, 71, p. 4675, 2006 DOI: 10.1021/jo0601821

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