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PULCHINENOSIDE B4

Basic information Safety Supplier Related

PULCHINENOSIDE B4 Basic information

Product Name:
PULCHINENOSIDE B4
Synonyms:
  • PULCHINENOSIDE B4
  • Anemoside B4 Pulchinenoside B4
  • Chinensioside A
  • Pulchinenoside C
  • Anemoside B4
  • Pulsatilla saponin B4
  • Pulchinenoside B4, 98%, from Pulsatilla chinensis (Bunge) Regel
  • AnemosideB4 129741-57-7
CAS:
129741-57-7
MF:
C59H96O26
MW:
1221.38
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
129741-57-7.mol
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PULCHINENOSIDE B4 Chemical Properties

Melting point:
208-215℃
Density 
1.48
solubility 
DMSO : 125 mg/mL (102.34 mM; Need ultrasonic)
form 
Powder
pka
12.50±0.70(Predicted)
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PULCHINENOSIDE B4 Usage And Synthesis

Description

Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.

Uses

Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory.

PULCHINENOSIDE B4Supplier

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