tetrahydroharmine Chemical Properties

Melting point:

199 °C

Boiling point:

399.2±37.0 °C(Predicted)

Density 

1.145±0.06 g/cm3(Predicted)

storage temp. 

Amber Vial, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

18.03±0.40(Predicted)

color 

White to Off-White

Stability:

Light Sensitive

tetrahydroharmine Usage And Synthesis

Description

This carboline alkaloid is present in Banisteria caapi, a plant indigenous toSouth America. It is dextrorotatory with [o:]l>s + 32° (c 1.0, CHCI3). One methoxyl group, a methyl group and two imino groups are present in the molecule.

Uses

Tetrahydroharmine is a β-Carboline derivative. β-Carboline alkaloids are inhibitors of human monoamine oxidase enzymes. β-carboline derivatives were also reported to have antiviral and fungicidal activity. Tetrahydroharmine is related to 3,4-Dihydroharmine (D449718).

References

Hochstein, Paradies., J. Arner. Chern. Soc., 79, 5735 (1957)
Bernauer., Helv. Chirn. Acta, 47, 1075 (1960)
Koblicova, Trojanek., Chern. Ind., 1342 (1966)

tetrahydroharmine(17019-01-1)Related Product Information

• Metoserpate
• RESCINNAMINE
• SYROSINGOPINE
• ARICINE
• Fumitremorgin A
• tetrahydroharmine
• Reserpine
• Mefeserpine
• bietaserpine
• FUMITREMORGIN C
• (-)-ISORESERPINE
• Rescimetol
• fumitremorgin B
• RESERPINIC ACID HCL
• 11-methoxymacusine A
• 2-METHYL TETRAHYDROHARMOL HCL
• 10,11-Dimethoxy-3-isotetrahydroalstonique acide hydrazide diphosphate [French]
• AKOS 237-158