destomycin A Chemical Properties

Melting point:

180-190° (dec)

alpha 

D22 +7° (c = 2)

Boiling point:

608.13°C (rough estimate)

Density 

1.4252 (rough estimate)

refractive index 

1.6300 (estimate)

pka

12.53±0.10(Predicted)

CAS DataBase Reference

14918-35-5

Safety Information

Toxicity

LD50 in mice (after 2-week observation) (mg/kg): 5-10 i.v.; 50-100 orally (Kondo, 1965)

destomycin A Usage And Synthesis

Description

Destomycin A was found in the culture broth of Streptomyces rimofaciens by Meiji Seika Kaisha in 1965 in the course of screening for water-soluble and basic antibiotics, such as aminoglycosides. It shows activity against a variety of gram-positive and gram-negative bacteria as well as fungi and, more interestingly, against helminths. Destomycin A has been used to treat helminth infections in swine and poultry.

Chemical Properties

White powder, easily soluble in water and lower alcohol, and is extremely stable in sealed, moisture-proof and room temperature storage.

Uses

Demycin A is currently mainly used in feed to prevent and control digestive tract parasites in chickens and pigs.

Synthesis

Demycin A is produced by fermentation of Actinomyces rimofaciens nov.sp.

destomycin A(14918-35-5)Related Product Information

• Moxifloxacin
• Glutathione
• Ampicillin
• Urea
• Metronidazole
• Maduramicin
• Triethyl orthoacetate
• FEMA 2542
• destomycin A
• Trimethyl orthopropionate
• A 396-I
• Triethyl orthopropionate
• Triethyl orthobutyrate
• 2-METHOXY-1,3-DIOXOLANE
• Trimethyl orthobutyrate