isoliquiritin apioside
isoliquiritin apioside Basic information
- Product Name:
- isoliquiritin apioside
- Synonyms:
-
- isoliquiritin apioside
- (2E)-3-[4-[(2-O-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-2-propen-1-one
- Soliquiritin apioside
- Neolicuroside
- (E)-3-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
- 2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-
- isoliquiritin apioside USP/EP/BP
- (E)-3-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
- CAS:
- 120926-46-7
- MF:
- C26H30O13
- MW:
- 550.51
- Mol File:
- 120926-46-7.mol
isoliquiritin apioside Chemical Properties
- Boiling point:
- 901.0±65.0 °C(Predicted)
- Density
- 1.63
- storage temp.
- -20°C, protect from light
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 7.46±0.35(Predicted)
- color
- Yellow to orange
- biological source
- plant
- Water Solubility
- water: slightly soluble
- InChIKey
- VMMVZVPAYFZNBM-KVFWHIKKSA-N
- SMILES
- O([C@@H]1OC[C@]([C@H]1O)(O)CO)[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC1C=CC(=CC=1)/C=C/C(C1C=CC(=CC=1O)O)=O)CO)O)O
- CAS DataBase Reference
- 120926-46-7
isoliquiritin apioside Usage And Synthesis
Chemical Properties
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice.
Uses
Isoliquiritin apioside can be used to resist myocardial ischemia and inhibit the proliferation of HIV.
Definition
ChEBI: Neolicuroside is a member of flavonoids and a glycoside.
Biological Activity
Neolicuroside modulates signaling pathways (e.g., MAPK, NF-KB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).
IC 50
MMP9; NF-κB; p38 MAPK
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isoliquiritin apioside(120926-46-7)Related Product Information
- Glycyroside
- 5,7-Dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one
- neoglycyrol
- SeMilicoisoflavone B
- Liquiritin apioside
- LICOFLAVONOL
- LICOISOFLAVONE A
- 4H-1-Benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)phenyl)-2,3-dihy dro-5,7-dihydroxy-, (2S)-
- Licorice glycoside C2
- 4,4'-DIHYDROXY-2-METHOXYCHALCONE
- Apigenin 7-glucoside
- Liguiritigenin-7-O-D-apiosyl-4’-O-D-glucoside
- Isoliquiritigenin
- LICOCHALCONE-A
- LIQUIRITIGENIN
- LIQUIRITIN(SH)
- ISOLIQUIRITIN
- isoliquiritin apioside