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(S)-3-Fluoro-pyrrolidine hydrochloride

Basic information Safety Supplier Related

(S)-3-Fluoro-pyrrolidine hydrochloride Basic information

Product Name:
(S)-3-Fluoro-pyrrolidine hydrochloride
Synonyms:
  • (3S)-3-fluoropyrrolidin-1-ium
  • (S)-3-FLUORO-PYRROLIDINE HCL
  • (S)-(+)-3-FLUOROPYRROLIDINE HYDROCHLORIDE
  • (S)-3-FLUOROPYRROLIDINE HYDROCHLORIDE
  • (R)-3-FLUORO-PYRROLIDINE HCL
  • S-(+)-3-Fluoropyrrolidinehydrochloride98%ee
  • 3(S)-fluoropyrrolidine(HCl)
  • (S)-3-Fluoropyrrolidine h...
CAS:
136725-53-6
MF:
C4H9ClFN
MW:
125.57
Product Categories:
  • Asymmetric Synthesis
  • Building Blocks
  • Chemical Synthesis
  • Chiral Building Blocks
  • Fluorinated Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • Other Fluorinated Heterocycles
Mol File:
136725-53-6.mol
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(S)-3-Fluoro-pyrrolidine hydrochloride Chemical Properties

Melting point:
183-187 °C(lit.)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Powder or Crystalline Powder
color 
White to pale brown
optical activity
[α]20/D +8°, c = 1% in methanol
InChIKey
LENYOXXELREKGZ-WCCKRBBISA-N
CAS DataBase Reference
136725-53-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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(S)-3-Fluoro-pyrrolidine hydrochloride Usage And Synthesis

Chemical Properties

Light pink to purple solid

Uses

(S)-(+)-3-Fluoropyrrolidine, HCl

Uses

(S)-(+)-3-Fluoropyrrolidine hydrochloride can be employed as a building block for the preparation of:

  • Fluorinated pyrrolidine derivatives of cyclohexylglycine amides as potential inhibitors for dipeptidyl peptidase IV.
  • Fluoropyrrolidine contaning N--ethylurea pyrazole derivatives as potential and selective inhibitors for Trypanosoma brucei and Trypanosoma cruzi parasitic causative agents.
  • Urea derivatives of (S)-2-(3,4-difluorophenyl)-5-(3-fluoro-N-pyrrolidylamido)benzothiazole as potent antitrypanosomal agents.

Uses

The derived amide acts as an inhibitor of dipeptidyl peptidase IV.1

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