horminone
horminone Basic information
- Product Name:
- horminone
- Synonyms:
-
- horminone
- 7ALPHA,12-DIHYDROXY-8,12-ABIETADIENE-11,14-DIONE
- (4bS)-1,4,4b,5,6,7,8,8aβ,9,10-Decahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
- (4bS)-4b,5,6,7,8,8aβ,9,10-Octahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
- 7α,12-Dihydroxyabieta-8,12-diene-11,14-dione
- 7α-Hydroxyroyleanone
- 1,4-Phenanthrenedione, 4B,5,6,7,8,8A,9,10-octahydro-3,10-dihydroxy-4B,8,8-trimethyl-2-(1-methylethyl)-
- Aids031165
- CAS:
- 21887-01-4
- MF:
- C20H28O4
- MW:
- 332.43
- Mol File:
- 21887-01-4.mol
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horminone Chemical Properties
- Melting point:
- 178 °C
- Boiling point:
- 469.3±45.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 4.50±1.00(Predicted)
- color
- Yellow
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horminone Usage And Synthesis
Uses
Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity[1].
Definition
ChEBI: An abietane diterpenoid that is abieta-8,12-diene substituted by hydroxy groups at positions 7 and 12 and oxo groups at positions 11 and 14 (the 7alpha stereoisomer) .
target
DNA/RNA Synthesis | NADPH-oxidase | Antifection
References
[1] Inés Nicolás, et al. Theoretical study of the structure and antimicrobial activity of horminone. Theoretical Biochemistry and Biophysics. 2003.
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