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horminone

Basic information Safety Supplier Related

horminone Basic information

Product Name:
horminone
Synonyms:
  • horminone
  • 7ALPHA,12-DIHYDROXY-8,12-ABIETADIENE-11,14-DIONE
  • (4bS)-1,4,4b,5,6,7,8,8aβ,9,10-Decahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
  • (4bS)-4b,5,6,7,8,8aβ,9,10-Octahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
  • 7α,12-Dihydroxyabieta-8,12-diene-11,14-dione
  • 7α-Hydroxyroyleanone
  • 1,4-Phenanthrenedione, 4B,5,6,7,8,8A,9,10-octahydro-3,10-dihydroxy-4B,8,8-trimethyl-2-(1-methylethyl)-
  • Aids031165
CAS:
21887-01-4
MF:
C20H28O4
MW:
332.43
Mol File:
21887-01-4.mol
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horminone Chemical Properties

Melting point:
178 °C
Boiling point:
469.3±45.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
4.50±1.00(Predicted)
color 
Yellow
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horminone Usage And Synthesis

Uses

Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity[1].

Definition

ChEBI: An abietane diterpenoid that is abieta-8,12-diene substituted by hydroxy groups at positions 7 and 12 and oxo groups at positions 11 and 14 (the 7alpha stereoisomer) .

target

DNA/RNA Synthesis | NADPH-oxidase | Antifection

References

[1] Inés Nicolás, et al. Theoretical study of the structure and antimicrobial activity of horminone. Theoretical Biochemistry and Biophysics. 2003.

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